SCHEMBL1032899

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1036232	0.89	SIRT2 (0.50)	SIRT2ABL1MPLFGFR4MAPKAPK2
	SCHEMBL1030617	0.86	ABL1 (0.52)	SIRT2ABL1DYRK1ATSHRNPSR1
	SCHEMBL1034603	0.86	ALOX15 (0.59)	SIRT2DYRK1AALOX15TSHRCASP1
	SCHEMBL1032167	0.85	MEN1 (0.48)	SIRT2ABL1MPLOPRM1KCNH2
	SCHEMBL1034164	0.84	SIRT2 (0.54)	SIRT2ABL1ALOX15TSHRCASP1
	SCHEMBL1031251	0.83	SIRT2 (0.56)	SIRT2ABL1ALOX15TSHRCASP1
	SCHEMBL1033187	0.82	ABL1 (0.47)	ABL1OPRM1KCNH2FYNDHODH
	SCHEMBL12673087	0.82	DHODH (0.59)	SIRT2ABL1ALOX15TSHRCASP1
	SCHEMBL13187920	0.81	SIRT2 (0.48)	SIRT2ABL1DYRK1AALOX15TSHR
	SCHEMBL1029914	0.81	NPC1 (0.52)	ABL1DYRK1AALOX15TSHRMPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.