SCHEMBL1032902

SCHEMBL1032902

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CCC4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.68
▸ KMT2A Q03164 2/20 0.68
▸ USP2 O75604 2/20 0.68
▸ ALDH1A1 P00352 2/20 0.68
▸ MAPT P10636 1/20 0.68
▸ ALOX15 P16050 1/20 0.68
▸ CYP3A4 P08684 1/20 0.63
▸ DHCR24 Q15392 6/20 0.51
▸ CDC25B P30305 2/20 0.46
▸ CDC25A P30304 1/20 0.46
▸ SRD5A1 P18405 6/20 0.45
▸ THRB P10828 1/20 0.43
▸ SRD5A2 P31213 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14415422 1.00 MEN1 (0.68) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL12883833 1.00 MEN1 (0.68) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL13077330 1.00 MEN1 (0.68) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL12869820 1.00 MEN1 (0.68) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL7797018 1.00 MEN1 (0.68) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL12884155 1.00 MEN1 (0.68) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL12869828 0.91 CYP3A4 (0.60) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL12869769 0.91 CYP3A4 (0.60) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL12869841 0.91 CYP3A4 (0.60) MEN1KMT2AUSP2ALDH1A1MAPT
SCHEMBL12869768 0.91 CYP3A4 (0.60) MEN1KMT2AUSP2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10078091-B2 Analysis of a panel of cerebrotendinous xanthomatosis biomarkers using site specific derivation and LC/MS/MS workflow DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) 2018-09-18 — — US claimed
EP-2850430-B1 ANALYSIS OF A PANEL OF CEREBROTENDINOUS XANTHOMATOSIS BIOMARKERS USING SITE SPECIFIC DERIVATION AND LC/MS/MS WORKFLOW DH TECHNOLOGIES DEV PTE LTD (SG) 2017-04-19 — — EP claimed
US-20150323554-A1 ANALYSIS OF A PANEL OF CEREBROTENDINOUS XANTHOMATOSIS BIOMARKERS USING SITE SPECIFIC DERIVATION AND LC/MS/MS WORKFLOW DH TECHNOLOGIES DEVELOPMENT PTE. LTD (SG) 2015-11-12 — — US claimed
EP-2850430-A1 ANALYSIS OF A PANEL OF CEREBROTENDINOUS XANTHOMATOSIS BIOMARKERS USING SITE SPECIFIC DERIVATION AND LC/MS/MS WORKFLOW Dh Technologies Development Pte. Ltd. (SG) 2015-03-25 — — EP claimed
WO-2013171568-A1 ANALYSIS OF A PANEL OF CEREBROTENDINOUS XANTHOMATOSIS BIOMARKERS USING SITE SPECIFIC DERIVATION AND LC/MS/MS WORKFLOW DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) 2013-11-21 — — WO claimed
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities THE BROAD INSTITUTE, INC. (US) 2026-03-17 — — US disclosed
US-20250376656-A1 MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-12-11 — — US disclosed
US-20220228190-A1 MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-07-21 — — US disclosed
CN-110313532-A A kind of pilose antler beauty treatment mind easing tea and preparation method thereof 西安文理学院 2019-10-11 — — CN disclosed
US-10078091-B2 Analysis of a panel of cerebrotendinous xanthomatosis biomarkers using site specific derivation and LC/MS/MS workflow DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) 2018-09-18 — — US disclosed
EP-2850430-B1 ANALYSIS OF A PANEL OF CEREBROTENDINOUS XANTHOMATOSIS BIOMARKERS USING SITE SPECIFIC DERIVATION AND LC/MS/MS WORKFLOW DH TECHNOLOGIES DEV PTE LTD (SG) 2017-04-19 — — EP disclosed
US-20150323554-A1 ANALYSIS OF A PANEL OF CEREBROTENDINOUS XANTHOMATOSIS BIOMARKERS USING SITE SPECIFIC DERIVATION AND LC/MS/MS WORKFLOW DH TECHNOLOGIES DEVELOPMENT PTE. LTD (SG) 2015-11-12 — — US disclosed
EP-2850430-A1 ANALYSIS OF A PANEL OF CEREBROTENDINOUS XANTHOMATOSIS BIOMARKERS USING SITE SPECIFIC DERIVATION AND LC/MS/MS WORKFLOW Dh Technologies Development Pte. Ltd. (SG) 2015-03-25 — — EP disclosed
WO-2013171568-A1 ANALYSIS OF A PANEL OF CEREBROTENDINOUS XANTHOMATOSIS BIOMARKERS USING SITE SPECIFIC DERIVATION AND LC/MS/MS WORKFLOW DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) 2013-11-21 — — WO disclosed
EP-2269630-A1 Novel anti-nematode therapies targetting STRM-1 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2011-01-05 — — EP disclosed
WO-2010146062-A2 NOVEL ANTI-HELMINTHIC THERAPIES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2010-12-23 — — WO disclosed
US-20100009927-A1 Anti-Inflammatory and Anti-Allergy Extracts from Nettle HERBALSCIENCE GROUP LLC (US) 2010-01-14 — — US disclosed
US-20020183283-A1 Meiosis regulating compounds FAARUP PETER (DK) 2002-12-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183283-A1 Meiosis regulating compounds SREBF2, SREBF1, TRIP13 MEN1 2167/4885KMT2A 1254/4885USP2 1879/4885
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities STUB1, SAMM50, CD14 MEN1 4321/4885KMT2A 4140/4885USP2 806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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