Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660719 | 0.94 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL28398818 | 0.94 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL29122639 | 0.94 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL20660561 | 0.94 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL10620286 | 0.94 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL20660653 | 0.94 | OPRK1 (0.59) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL27476119 | 0.90 | OPRK1 (0.66) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL4121702 | 0.88 | OPRK1 (0.62) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 | |
| SCHEMBL31570078 | 0.87 | POLB (0.58) | OPRK1KMT2AMEN1HSD17B10LMNA | |
| SCHEMBL11284305 | 0.86 | OPRK1 (0.61) | OPRK1KMT2AMEN1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222296-B2 | Conjugates comprising a GABA- or glycine compound, pharmaceutical compositions and combinations thereof and their use in treating CNS disorders | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-07-17 | — | — | US | disclosed |
| US-7723529-B2 | Process for preparing nitrooxy esters, nitrooxy thioesters nitrooxy carbonates and nitrooxy thiocarbinates, intermediates useful in said process and preparation thereof | NICOX S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | NICOX S.A. (FR) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238882-A1 | Process for Preparing Nitrooxy Esters, Nitrooxy Thioesters Nitrooxy Carbonates and Nitrooxy Thiocarbinates, Intermediates Useful in Said Process and Preparation Thereof | OTUB1, TET1, TET3 | OPRK1 3213/4885KMT2A 2729/4885MEN1 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.