Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284305 | 0.95 | OPRK1 (0.61) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL11275255 | 0.89 | OPRK1 (0.54) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL10329430 | 0.88 | OPRK1 (0.62) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL8223629 | 0.86 | KMT2A (0.60) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL12987121 | 0.85 | KMT2A (0.68) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL20660653 | 0.85 | OPRK1 (0.59) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL20660561 | 0.85 | OPRK1 (0.59) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL20660719 | 0.85 | OPRK1 (0.59) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL3807668 | 0.85 | KMT2A (0.58) | OPRK1KMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL10620286 | 0.85 | OPRK1 (0.59) | OPRK1KMT2AMEN1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207411-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | SEAPORT THERAPEUTICS, INC. | 2024-06-27 | — | — | US | disclosed |
| EP-4306524-A2 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | PureTech LYT, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2019046491-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | ARIYA THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| US-7629368-B2 | Nitroderivatives as drugs for diseases having an inflammatory basis | NICOX S.A. (FR) | 2009-12-08 | — | — | US | disclosed |
| US-20090075952-A1 | NITRODERVIATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NICOX S.A. | 2009-03-19 | — | — | US | disclosed |
| US-7465803-B2 | Nitroderivatives as drugs for diseases having an inflammatory basis | NICOX S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-7442826-B2 | Process for the preparation of nitrooxyderivatives of paracetamol | NICOX S.A. (FR) | 2008-10-28 | — | — | US | disclosed |
| US-20080194651-A1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NICOX S.A. | 2008-08-14 | — | — | US | disclosed |
| WO-2008096128-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES 2 | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008096128-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES 2 | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
| EP-1339665-B1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NICOX SA (FR) | 2007-12-19 | — | — | EP | disclosed |
| US-20070197499-A1 | Pharmaceutical compounds | NICOX S.A. | 2007-08-23 | — | — | US | disclosed |
| US-20070149801-A1 | New process for the preparation of nitrooxyderivatives of paracetamol | NICOX S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| US-20070149801-A1 | New process for the preparation of nitrooxyderivatives of paracetamol | NICOX S.A. (FR) | 2007-06-28 | — | — | US | disclosed |
| CN-1923797-A | Pharmaceutical compounds | NICOX SA (FR) | 2007-03-07 | — | — | CN | disclosed |
| CN-1289466-C | Pharmaceutical compounds | NICOX SA (FR) | 2006-12-13 | — | — | CN | disclosed |
| US-20040023933-A1 | Nitroderivatives as drugs for diseases having an inflammatory basis | NICOX S.A. (FR) | 2004-02-05 | — | — | US | disclosed |
| EP-1339665-A1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | Nicox S.A. (FR) | 2003-09-03 | — | — | EP | disclosed |
| CN-1433396-A | Pharmaceutical compounds | NICOX SA (FR) | 2003-07-30 | — | — | CN | disclosed |
| WO-2002030866-A1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NICOX S.A. (FR) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197499-A1 | Pharmaceutical compounds | NR0B2, NR0B1, CYP11B2 | OPRK1 24/4885KMT2A 4577/4885MEN1 1637/4885 |
| US-20070149801-A1 | New process for the preparation of nitrooxyderivatives of paracetamol | CYP2E1, CYP3A43, CYP3A5 | OPRK1 69/4885KMT2A 4423/4885MEN1 4454/4885 |
| US-20090075952-A1 | NITRODERVIATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NR3C1, NR0B1, NOX1 | OPRK1 82/4885KMT2A 3396/4885MEN1 4805/4885 |
| US-20080194651-A1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NR3C1, NR2E1, CYP2E1 | OPRK1 120/4885KMT2A 2845/4885MEN1 4552/4885 |
| US-20040023933-A1 | Nitroderivatives as drugs for diseases having an inflammatory basis | TPMT, NOX1, CBR1 | OPRK1 412/4885KMT2A 2615/4885MEN1 4828/4885 |
| US-20240207411-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | LIPA, MALT1, SGMS1 | OPRK1 3695/4885KMT2A 2872/4885MEN1 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.