Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 19/20 | 0.60 |
| ▸ | ITGB7 | P26010 | 19/20 | 0.60 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.60 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10329614 | 0.89 | ITGA4 (0.65) | ITGA4ITGB7ITGB1 | |
| SCHEMBL16489169 | 0.89 | ITGA4 (0.65) | ITGA4ITGB7ITGB1 | |
| SCHEMBL13819258 | 0.89 | ITGA4 (0.63) | ITGA4ITGB7ITGB1 | |
| SCHEMBL13819338 | 0.87 | ITGA4 (0.69) | ITGA4ITGB7ITGB1 | |
| SCHEMBL6015064 | 0.87 | ITGA4 (0.69) | ITGA4ITGB7ITGB1 | |
| SCHEMBL13819257 | 0.85 | ITGA4 (0.58) | ITGA4ITGB7ITGB1 | |
| SCHEMBL17117095 | 0.85 | ITGA4 (0.67) | ITGA4ITGB7ITGB1 | |
| SCHEMBL10329628 | 0.85 | ITGA4 (0.66) | ITGA4ITGB7ITGB1 | |
| SCHEMBL12955399 | 0.84 | ITGA4 (0.85) | ITGA4ITGB7ITGB1 | |
| SCHEMBL10329624 | 0.84 | ITGA4 (0.85) | ITGA4ITGB7ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518441-B2 | Solid dispersions or solid dispersion pharmaceutical preparations of phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2013-08-27 | — | — | US | disclosed |
| US-8518441-B2 | Solid dispersions or solid dispersion pharmaceutical preparations of phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2013-08-27 | — | — | US | disclosed |
| US-8426588-B2 | Phenylalanine derivatives | AJINOMOTO CO, INC. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8426588-B2 | Phenylalanine derivatives | AJINOMOTO CO, INC. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20120253041-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120253041-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-8222405-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2012-07-17 | — | — | US | disclosed |
| US-8222405-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20110065918-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20110065918-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2011-03-17 | — | — | US | disclosed |
| US-7872125-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-7872125-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2011-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065918-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, ITGA4, ITGAV | ITGA4 2/4885ITGB7 20/4885ITGB1 13/4885 |
| US-20120253041-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, ITGA4, ITGAV | ITGA4 2/4885ITGB7 20/4885ITGB1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.