SCHEMBL10329671

SCHEMBL10329671

Cc1ccc(-c2ccc(-c3ccc(-c4ccc(-c5ccc(-c6nc7sc(-c8ccc(C)s8)nc7s6)s5)s4)s3)s2)s1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.42
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 3/20 0.42
MAPT P10636 3/20 0.42
GFER P55789 1/20 0.42
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
KDM4E B2RXH2 2/20 0.37
TP53 P04637 2/20 0.37
HPGD P15428 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
HSF1 Q00613 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10329666 1.00 NPC1 (0.42) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL10329684 1.00 NPC1 (0.42) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL10301436 0.96 NPC1 (0.45) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL12436843 0.81 RAB9A (0.45) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL12982161 0.81 NPC1 (0.50) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL12170048 0.81 NPC1 (0.50) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL120939 0.81 NPC1 (0.50) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL12982405 0.81 NPC1 (0.50) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL11997754 0.81 NPC1 (0.50) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL10329680 0.79 PGR (0.41) NPC1ALDH1A1HSD17B10MAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8222633-B2 Organic transistor using thiazolothiazole derivatives and method for fabricating the same LG CHEM, LTD. (KR) 2012-07-17 US disclosed
US-20100012930-A1 ORGANIC TRANSISTOR USING THIAZOLOTHIAZOLE DERIVATIVES AND METHOD FOR FABRICATING THE SAME LG CHEM, LTD. (KR) 2010-01-21 US disclosed