Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10301436 | 0.83 | NPC1 (0.45) | PGRNPC1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9927249 | 0.82 | APP (0.48) | PGRAPPNPC1ALDH1A1HSD17B10 | |
| SCHEMBL10300218 | 0.80 | APP (0.46) | PGRAPPNPC1ALDH1A1HSD17B10 | |
| SCHEMBL13424304 | 0.80 | APP (0.46) | PGRAPPNPC1ALDH1A1HSD17B10 | |
| SCHEMBL10329684 | 0.79 | NPC1 (0.42) | PGRAPPNPC1ALDH1A1HSD17B10 | |
| SCHEMBL10329671 | 0.79 | NPC1 (0.42) | PGRAPPNPC1ALDH1A1HSD17B10 | |
| SCHEMBL10329666 | 0.79 | NPC1 (0.42) | PGRAPPNPC1ALDH1A1HSD17B10 | |
| SCHEMBL13801070 | 0.79 | ALOX5 (0.53) | APPNPC1ALDH1A1MAPTALOX5 | |
| SCHEMBL13376691 | 0.78 | APP (0.50) | PGRAPPNPC1ALDH1A1HSD17B10 | |
| SCHEMBL147842 | 0.76 | HSD17B1 (0.44) | PGRAPPNPC1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222633-B2 | Organic transistor using thiazolothiazole derivatives and method for fabricating the same | LG CHEM, LTD. (KR) | 2012-07-17 | — | — | US | disclosed |
| US-20100012930-A1 | ORGANIC TRANSISTOR USING THIAZOLOTHIAZOLE DERIVATIVES AND METHOD FOR FABRICATING THE SAME | LG CHEM, LTD. (KR) | 2010-01-21 | — | — | US | disclosed |