SCHEMBL10330491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8432931	0.94	TSHR (0.47)	TSHRKDM4EMEN1KMT2ADUSP3
	SCHEMBL11882411	0.88	TSHR (0.44)	TSHRKDM4EMEN1KMT2ADUSP3
	SCHEMBL8764057	0.88	TSHR (0.50)	TSHRKDM4EMEN1KMT2ADUSP3
	SCHEMBL11628856	0.87	TSHR (0.60)	TSHRKDM4EMEN1KMT2ADUSP3
	SCHEMBL8421411	0.85	TSHR (0.45)	TSHRKDM4EMEN1KMT2ALMNA
	SCHEMBL4993413	0.84	TSHR (0.50)	TSHRKDM4EMEN1KMT2ADUSP3
	SCHEMBL9498035	0.84	TSHR (0.53)	TSHRKDM4EMEN1KMT2ADUSP3
	SCHEMBL29009582	0.84	TSHR (0.57)	TSHRKDM4EMEN1KMT2ADUSP3
	SCHEMBL3972903	0.83	TSHR (0.49)	TSHRKDM4EMEN1KMT2ADUSP3
	SCHEMBL1254411	0.83	TSHR (0.52)	TSHRKDM4EMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.