Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.55 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.54 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539026 | 1.00 | LMNA (0.57) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL25172916 | 1.00 | LMNA (0.57) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL22439030 | 1.00 | LMNA (0.57) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL17349905 | 1.00 | LMNA (0.57) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL7528179 | 0.95 | LMNA (0.62) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7340690 | 0.94 | RARB (0.56) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL1667448 | 0.93 | PLA2G4A (0.56) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL25456590 | 0.93 | PLA2G4A (0.56) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL25176144 | 0.90 | PLA2G4A (0.53) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL7626988 | 0.88 | PLA2G4B (0.56) | LMNAL3MBTL1S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942174-A | ALKOXYARYLCARBOXYLIC ACIDS OR ESTERS OR SALTS FOR SKIN DISORDERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0315914-A2 | Sebosuppressive topic preparations | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-05-17 | — | — | EP | disclosed |