Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25172916 | 0.95 | LMNA (0.57) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL17349905 | 0.95 | LMNA (0.57) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL22439030 | 0.95 | LMNA (0.57) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL6539026 | 0.95 | LMNA (0.57) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL10334162 | 0.95 | LMNA (0.57) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7340690 | 0.93 | RARB (0.56) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL28588481 | 0.92 | LMNA (0.56) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL14162906 | 0.89 | ALDH1A1 (0.60) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL28543599 | 0.89 | ADRB2 (0.54) | LMNAL3MBTL1ADRB2ADRB1FFAR1 | |
| SCHEMBL25176144 | 0.88 | PLA2G4A (0.53) | LMNAL3MBTL1KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002015691-A1 | USE FOR CONIFER SAPLING PROTECTION AGAINST INSECT ATTACK | ROBIGUS AB (SE) | 2002-02-28 | — | — | WO | claimed |
| EP-2886530-A1 | ORALLY ADMINISTRABLE VIRIDIOFUNGIN DERIVATIVE HAVING ANTI-HCV ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 2015-06-24 | — | — | EP | disclosed |
| WO-2002015691-A1 | USE FOR CONIFER SAPLING PROTECTION AGAINST INSECT ATTACK | ROBIGUS AB (SE) | 2002-02-28 | — | — | WO | disclosed |
| EP-0588785-A1 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-03-30 | — | — | EP | disclosed |
| US-5185363-A | Administering for treatment of inflammatory diseases | ABBOTT LABORATORIES (US) | 1993-02-09 | — | — | US | disclosed |
| EP-0588785-A4 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS. | ABBOTT LAB (US) | 1991-12-30 | — | — | EP | disclosed |
| WO-1990012008-A1 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0292699-A2 | Urea based lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-11-30 | — | — | EP | disclosed |