Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10334864 | 0.93 | CYP3A4 (0.46) | CYP3A4CYP2D6ALDH1A1POLBMEN1 | |
| SCHEMBL10334648 | 0.90 | HTT (0.46) | LMNASMN1; SMN2CYP3A4CYP2D6KMT2A | |
| SCHEMBL10334725 | 0.90 | NPSR1 (0.45) | SMN1; SMN2CYP3A4CYP2D6ALDH1A1POLB | |
| SCHEMBL2488944 | 0.88 | LMNA (0.50) | LMNACYP3A4CYP2D6ALDH1A1POLB | |
| SCHEMBL10334748 | 0.87 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL10334657 | 0.85 | PRKCA (0.47) | LMNAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9292634 | 0.84 | KCNN4 (0.49) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10334190 | 0.81 | MAPT (0.46) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10335674 | 0.80 | RXFP1 (0.44) | LMNASMN1; SMN2CYP3A4ALDH1A1MEN1 | |
| SCHEMBL27690538 | 0.80 | CYP3A4 (0.44) | LMNACYP3A4CYP2D6ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |