Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27690538 | 0.91 | CYP3A4 (0.44) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL10334703 | 0.90 | CYP3A4 (0.54) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL15310068 | 0.88 | CYP3A4 (0.58) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL10334641 | 0.88 | LMNA (0.43) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL10335024 | 0.88 | MEN1 (0.53) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL341296 | 0.86 | PIN1 (0.51) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL10334767 | 0.85 | CYP3A4 (0.46) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9292635 | 0.81 | CYP3A4 (0.43) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL13481194 | 0.81 | LMNA (0.45) | LMNACYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL13481195 | 0.81 | LMNA (0.45) | LMNACYP3A4CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321000-A | Benzhydryl compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | claimed |
| EP-2470504-B1 | SYNTHESIS OF PROPIVERINE HYDROCHLORIDE | ANDAGAR RAMAKRISHNA RAMESHA (IN) | 2013-10-16 | — | — | EP | disclosed |
| EP-2470504-A1 | SYNTHESIS OF PROPIVERINE HYDROCHLORIDE | Andagar Ramakrishna, Ramesha (IN) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011114195-A1 | SYNTHESIS OF PROPIVERINE HYDROCHLORIDE | ANDAGAR RAMAKRISHNA RAMESHA (IN) | 2011-09-22 | — | — | WO | disclosed |
| US-5321000-A | Benzhydryl compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |