Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067536 | 0.82 | LMNA (0.54) | MEN1KMT2ASMN1; SMN2HDAC3HDAC11 | |
| SCHEMBL2791669 | 0.82 | LMNA (0.54) | MEN1KMT2ASMN1; SMN2HDAC3HDAC11 | |
| SCHEMBL19370711 | 0.82 | NPC1 (0.52) | CTSCMEN1KMT2ASMN1; SMN2HDAC3 | |
| SCHEMBL10335229 | 0.82 | LMNA (0.54) | MEN1KMT2ASMN1; SMN2HDAC3HDAC11 | |
| SCHEMBL8669058 | 0.81 | POLB (0.39) | MEN1KMT2ASMN1; SMN2HDAC3HDAC11 | |
| SCHEMBL19359517 | 0.81 | TRHR (0.47) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL19359515 | 0.81 | TRHR (0.47) | HDAC3HDAC11HDAC6HDAC1HDAC2 | |
| SCHEMBL29070774 | 0.79 | CTSC (0.80) | CTSC | |
| SCHEMBL9753650 | 0.79 | CTSC (0.80) | CTSC | |
| SCHEMBL11488813 | 0.79 | CTSC (0.80) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253882-A4 | ACYLATED CYANAMIDE COMPOSITION. | UNIV MINNESOTA (US) | 1990-06-27 | — | — | EP | claimed |
| US-4870056-A | DETERRENTS OF ALCOHOL ABUSE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-09-26 | — | — | US | claimed |
| EP-0253882-A1 | ACYLATED CYANAMIDE COMPOSITION | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1988-01-27 | — | — | EP | claimed |
| WO-1987004348-A1 | ACYLATED CYANAMIDE COMPOSITION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1987-07-30 | — | — | WO | claimed |
| US-4940816-A | Acylated cyanamide compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0253882-A4 | ACYLATED CYANAMIDE COMPOSITION. | UNIV MINNESOTA (US) | 1990-06-27 | — | — | EP | disclosed |
| US-4870056-A | DETERRENTS OF ALCOHOL ABUSE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-09-26 | — | — | US | disclosed |
| US-4726941-A | Acylated cyanamide composition for treating ethanol ingestion | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0253882-A1 | ACYLATED CYANAMIDE COMPOSITION | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1988-01-27 | — | — | EP | disclosed |
| WO-1987004348-A1 | ACYLATED CYANAMIDE COMPOSITION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1987-07-30 | — | — | WO | disclosed |