Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRHR | P34981 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607473 | 0.82 | POLB (0.38) | POLBSMN1; SMN2MEN1KMT2ATRHR | |
| SCHEMBL10335267 | 0.81 | CTSC (0.52) | SMN1; SMN2MEN1KMT2AHDAC3HDAC11 | |
| SCHEMBL11110153 | 0.80 | HDAC3 (0.36) | SMN1; SMN2TRHRHDAC3HDAC11HDAC6 | |
| SCHEMBL2190498 | 0.80 | CNR1 (0.41) | POLBSMN1; SMN2MEN1KMT2AHDAC3 | |
| SCHEMBL31672199 | 0.80 | TRHR (0.42) | POLBTRHRHDAC3HDAC11HDAC6 | |
| SCHEMBL10580958 | 0.79 | HDAC3 (0.40) | POLBSMN1; SMN2MEN1KMT2ATRHR | |
| SCHEMBL11238087 | 0.77 | TRHR (0.38) | POLBSMN1; SMN2MEN1KMT2ATRHR | |
| SCHEMBL2182635 | 0.77 | TRHR (0.38) | POLBSMN1; SMN2MEN1KMT2ATRHR | |
| SCHEMBL10661794 | 0.72 | HDAC3 (0.43) | POLBSMN1; SMN2MEN1KMT2ATRHR | |
| SCHEMBL25039712 | 0.72 | POLB (0.46) | POLBSMN1; SMN2MEN1KMT2ATRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883629-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | Emisphere Technologies, Inc. (US) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031938-A9 | OLIGOPEPTIDES FOR DRUG DELIVERY | — | 1997-11-20 | — | — | WO | disclosed |
| WO-1997031938-A1 | OLIGOPEPTIDES FOR DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 1997-09-04 | — | — | WO | disclosed |