Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2691885 | 0.84 | CA12 (0.43) | PRKCAPOLBGAANPSR1CHRNB2 | |
| SCHEMBL12076232 | 0.84 | ALOX15 (0.44) | PRKCAPOLBGAANPSR1CHRNB2 | |
| SCHEMBL10044201 | 0.82 | HMGCR (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL15121417 | 0.79 | PRKCA (0.39) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL7474619 | 0.79 | PRKCA (0.47) | PRKCAPOLBGAANPSR1ELANE | |
| SCHEMBL14175340 | 0.79 | PRKCA (0.47) | PRKCAPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL25891695 | 0.79 | PRKCA (0.47) | PRKCAPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL19742312 | 0.78 | PRKCA (0.41) | PRKCAPOLBGAANPSR1CHRNB2 | |
| SCHEMBL4258156 | 0.78 | POLB (0.48) | PRKCAPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL14175394 | 0.78 | PRKCA (0.42) | PRKCAPOLBGAANPSR1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902811-A | ANTIULCER AGENTS | SHIONOGI & CO., LTD. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0297923-A1 | Benzodioxane prostacyclin analogues, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |