Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.67 |
| ▸ | SOST | Q9BQB4 | 2/20 | 0.67 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SLCO1B3 | Q9NPD5 | 4/20 | 0.55 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.55 |
| ▸ | SLCO2B1 | O94956 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152781 | 0.93 | SOST (0.79) | XDHSOSTSYNJ2APPALDH1A1 | |
| SCHEMBL30152833 | 0.93 | SOST (0.79) | XDHSOSTSYNJ2APPALDH1A1 | |
| SCHEMBL15543702 | 0.93 | SOST (0.79) | XDHSOSTSYNJ2APPALDH1A1 | |
| SCHEMBL23743756 | 0.89 | ALDH1A1 (0.73) | XDHSOSTSYNJ2APPALDH1A1 | |
| SCHEMBL30256406 | 0.89 | XDH (0.76) | XDHSOSTSYNJ2APPALDH1A1 | |
| SCHEMBL4951008 | 0.89 | XDH (0.76) | XDHSOSTSYNJ2APPALDH1A1 | |
| SCHEMBL28460634 | 0.87 | CYP2C9 (0.68) | XDHSOSTALDH1A1SLCO1B3SLCO1B1 | |
| SCHEMBL23743745 | 0.87 | XDH (0.65) | XDHSOSTSYNJ2APPALDH1A1 | |
| SCHEMBL16887994 | 0.87 | XDH (0.73) | XDHSOSTSYNJ2ALDH1A1SLCO1B3 | |
| SCHEMBL21588102 | 0.85 | ALDH1A1 (0.71) | XDHSOSTSYNJ2APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290442-A4 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. | CHEMEX PHARMACEUTICALS INC (US) | 1990-07-03 | — | — | EP | disclosed |
| EP-0290442-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988003805-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | disclosed |