Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573659 | 0.95 | TYR (0.50) | TYRESR1ESR2CYP3A4HTT | |
| SCHEMBL9877534 | 0.79 | SKP2 (0.42) | TYRCYP3A4HTTMEN1KMT2A | |
| SCHEMBL14086599 | 0.77 | TYR (0.41) | TYRCYP3A4HTTMEN1KMT2A | |
| SCHEMBL8994657 | 0.77 | TYR (0.52) | TYRESR1ESR2CYP3A4HTT | |
| SCHEMBL30223636 | 0.76 | TYR (0.71) | TYRESR1ESR2CYP3A4HTT | |
| SCHEMBL30708512 | 0.76 | TYR (0.55) | TYRESR1ESR2CYP3A4HTT | |
| SCHEMBL26849 | 0.76 | TYR (0.71) | TYRESR1ESR2CYP3A4HTT | |
| SCHEMBL13360148 | 0.76 | PKM (0.48) | HTTTSHRTDP1EGFRCYP2D6 | |
| SCHEMBL17709428 | 0.76 | TYR (0.55) | TYRESR1ESR2CYP3A4HTT | |
| SCHEMBL11010019 | 0.75 | ALOX5 (0.40) | TYRCYP3A4HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474377-B1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | claimed |
| CN-1315779-C | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORP (US) | 2007-05-16 | — | — | CN | claimed |
| CN-1642900-A | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORP (US) | 2005-07-20 | — | — | CN | claimed |
| CN-1315779-C | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORP (US) | 2007-05-16 | — | — | CN | disclosed |
| CN-1642900-A | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORP (US) | 2005-07-20 | — | — | CN | disclosed |