Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722967 | 0.83 | ALDH1A1 (0.44) | GABRA1GABRB2ALDH1A1MAPTPOLB | |
| SCHEMBL1033550 | 0.79 | TYR (0.47) | TYRALDH1A1MAPTEGFRCYP3A4 | |
| SCHEMBL881183 | 0.77 | ALDH1A1 (0.34) | ALDH1A1MAPTPOLBEGFRGAA | |
| SCHEMBL14086599 | 0.77 | TYR (0.41) | SKP2TYRCTRCALDH1A1MAPT | |
| SCHEMBL30227228 | 0.76 | SKP2 (0.48) | SKP2TLR8TYRGABRPGABRD | |
| SCHEMBL39005 | 0.76 | SKP2 (0.48) | SKP2TLR8TYRGABRPGABRD | |
| SCHEMBL5377476 | 0.76 | SKP2 (0.48) | SKP2TLR8TYRGABRPGABRD | |
| SCHEMBL11573659 | 0.75 | TYR (0.50) | TYRMAPTCYP3A4PRSS1ACR | |
| SCHEMBL11010019 | 0.75 | ALOX5 (0.40) | TYRMAPTCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4455067 | 0.74 | SKP2 (0.52) | SKP2TLR8TYRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001171-A | Process, modified rubbers and rubber compositions | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4788229-A | BLENDING MIXTURES OF UNCURED ELASTOMERS AND FILLERS CONTAINING ELASTOMER-FILLER LINKAGE PROMOTERS; TIRES; FRICTION RESISTANCE; REDUCED HYSTERESIS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-11-29 | — | — | US | disclosed |