Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10816326 | 0.83 | LMNA (0.38) | MEN1KMT2AATMLMNAMTNR1A | |
| SCHEMBL27852911 | 0.79 | LMNA (0.40) | LMNAMTNR1AMTNR1BALDH1A1LTA4H | |
| SCHEMBL5511315 | 0.78 | CA4 (0.39) | MEN1KMT2AATMLMNAMTNR1A | |
| SCHEMBL11179700 | 0.78 | CYP1A2 (0.43) | LMNACYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL19769340 | 0.77 | KDM4E (0.42) | MEN1KMT2AATMLMNAMTNR1A | |
| SCHEMBL2453354 | 0.76 | LMNA (0.37) | LMNAMTNR1AMTNR1BALDH1A1LTA4H | |
| SCHEMBL7403074 | 0.75 | CA4 (0.36) | MEN1KMT2AATMLMNAMTNR1A | |
| SCHEMBL4582830 | 0.75 | GAA (0.43) | MEN1KMT2ALMNAMTNR1AMTNR1B | |
| SCHEMBL75998 | 0.74 | ALDH1A1 (0.39) | MEN1KMT2ALMNAMTNR1AMTNR1B | |
| SCHEMBL19758144 | 0.73 | KDM4E (0.36) | MEN1KMT2AATMLMNAMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380578-A1 | A PROCESS FOR THE PREPARATION OF 1,4-DISUBSTITUTED 2-BUTENES. | EASTMAN KODAK CO (US) | 1990-08-08 | — | — | EP | disclosed |
| WO-1989002883-A1 | A PROCESS FOR THE PREPARATION OF 1,4-DISUBSTITUTED 2-BUTENES | EASTMAN KODAK COMPANY (US) | 1989-04-06 | — | — | WO | disclosed |