SCHEMBL2453354

SCHEMBL2453354

OCC=CC(O)Oc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
LTA4H P09960 2/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
PPARG P37231 6/20 0.33
PPARA Q07869 6/20 0.33
AOC3 Q16853 1/20 0.32
SLC6A4 P31645 1/20 0.32
ALOX15 P16050 1/20 0.31
KCNA3 P22001 1/20 0.31
TSHR P16473 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
CYP2D6 P10635 1/20 0.31
ADRB3 P13945 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27852911 0.83 LMNA (0.40) LMNAALDH1A1LTA4HMTNR1AMTNR1B
SCHEMBL10816326 0.80 LMNA (0.38) LMNAMTNR1AMTNR1BPPARGPPARA
SCHEMBL10336142 0.76 MEN1 (0.42) LMNAALDH1A1LTA4HMTNR1AMTNR1B
SCHEMBL11179700 0.74 CYP1A2 (0.43) LMNAALDH1A1RECQLPPARGPPARA
SCHEMBL7763405 0.74 RCE1 (0.46) LMNAALDH1A1TSHRCYP2D6
SCHEMBL7763413 0.74 RCE1 (0.46) LMNAALDH1A1TSHRCYP2D6
SCHEMBL28449542 0.74 CYP1A2 (0.33) LMNAALDH1A1MTNR1AMTNR1B
SCHEMBL75998 0.71 ALDH1A1 (0.39) LMNAALDH1A1RECQLLTA4HMTNR1A
SCHEMBL11001287 0.69 LMNA (0.40) LMNAALDH1A1AOC3SLC6A4TSHR
SCHEMBL11001286 0.69 LMNA (0.40) LMNAALDH1A1AOC3SLC6A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0316548-A1 Use of compositions comprising a urethane prepolymer,a complex of methylenedianiline and an alcohol as ambiente temperature curable compositions. THE FIRESTONE TIRE & RUBBER COMPANY (US) 1989-05-24 EP claimed
US-4772676-A TIRE REPAIR THE FIRESTONE TIRE & RUBBER COMPANY (US) 1988-09-20 US claimed
US-10577450-B2 Storage stable activated prepolymer composition LANXESS SOLUTIONS US INC. (US) 2020-03-03 US disclosed
WO-2017053224-A1 STORAGE STABLE ACTIVATED PREPOLYMER COMPOSITION CHEMTURA CORPORATION (US) 2017-03-30 WO disclosed
US-20170088660-A1 STORAGE STABLE ACTIVATED PREPOLYMER COMPOSITION LANXESS SOLUTIONS US INC. 2017-03-30 US disclosed
US-20110223540-A1 GUMMING COMPOSITIONS WITH NANO-PARTICLES FOR IMPROVING SCRATCH SENSITIVITY IN IMAGE AND NON-IMAGE AREAS OF LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY 2011-09-15 US disclosed
WO-2010063763-A1 GUMMING COMPOSITIONS WITH NANO-PARTICLES FOR IMPROVING SCRATCH SENSITIVITY IN IMAGE AND NON-IMAGE AREAS OF LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 2010-06-10 WO disclosed
EP-2194429-A1 Gumming compositions with nano-particles for improving scratch sensitivity in image and non-image areas of lithographic printing plates EASTMAN KODAK COMPANY (US) 2010-06-09 EP disclosed
WO-2005037569-A1 PROCESS AND COMPOSITION FOR GUMMING LITHOGRAPHIC PRINTING PLATES KODAK POLYCHROME GRAPHICS GMBH (DE) 2005-04-28 WO disclosed
US-5691288-A MIXTURE OF POLYOL, STARCH OR DEXTRIN HYDROPHILIC FILM FORMING, ALKYLBENZENESULFONATE AMINE SALT, HYDROCARBONS,SURFACTANTS, ETHANOLAMINE, ACID AND WATER BAYER CORPORATION (US) 1997-11-25 US disclosed