Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509507 | 0.76 | ACHE (0.52) | ARGPR35ALDH1A1KDM4ECACNA1G | |
| SCHEMBL6644614 | 0.76 | AR (0.49) | ARGPR35HPGDSALDH1A1KDM4E | |
| SCHEMBL31432665 | 0.76 | AR (0.44) | ARGPR35HPGDSALDH1A1KDM4E | |
| SCHEMBL22954626 | 0.75 | LRRK2 (0.54) | LRRK2ARSLC6A4GAK | |
| SCHEMBL7927104 | 0.74 | AR (0.43) | LRRK2ARGPR35HPGDSALDH1A1 | |
| SCHEMBL443285 | 0.74 | TTR (0.52) | ARALDH1A1KDM4EUSP2EGFR | |
| SCHEMBL1614422 | 0.74 | AR (0.43) | ARGPR35HPGDSALDH1A1KDM4E | |
| SCHEMBL7927109 | 0.74 | ALDH1A1 (0.47) | ARGPR35HPGDSALDH1A1KDM4E | |
| SCHEMBL2093561 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4EUSP2 | |
| SCHEMBL8706878 | 0.73 | ACHE (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101265234-B | Method for synthesizing aditoprim | UNIV HUAZHONG AGRICULTURAL | 2010-11-03 | — | — | CN | claimed |
| CN-101265234-A | Method for synthesizing aditoprim | UNIV HUAZHONG AGRICULTURAL (CN) | 2008-09-17 | — | — | CN | claimed |
| US-4900859-A | Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde | HOFFMAN-LA ROCHE INC. (US) | 1990-02-13 | — | — | US | claimed |
| EP-0318826-A2 | Process for the preparation of 4-dimethylamino-3,5-dimethoxybenzaldehyde | F. HOFFMANN-LA ROCHE AG (CH) | 1989-06-07 | — | — | EP | claimed |
| JP-2000245-A | — | — | None | — | — | JP | disclosed |
| CN-101265234-B | Method for synthesizing aditoprim | UNIV HUAZHONG AGRICULTURAL | 2010-11-03 | — | — | CN | disclosed |
| CN-101265234-A | Method for synthesizing aditoprim | UNIV HUAZHONG AGRICULTURAL (CN) | 2008-09-17 | — | — | CN | disclosed |
| US-4900859-A | Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde | HOFFMAN-LA ROCHE INC. (US) | 1990-02-13 | — | — | US | disclosed |
| JP-H02245-A | PREPARATION OF 4-DIMETHYLAMIO-3,5-DIMETHOXYBENZALDEHYDE | F HOFFMANN LA ROCHE AG | 1990-01-05 | — | — | JP | disclosed |
| EP-0318826-A2 | Process for the preparation of 4-dimethylamino-3,5-dimethoxybenzaldehyde | F. HOFFMANN-LA ROCHE AG (CH) | 1989-06-07 | — | — | EP | disclosed |