Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846356 | 0.91 | EGFR (0.51) | TTRALBABL1BCRLMNA | |
| SCHEMBL17655654 | 0.90 | TTR (0.47) | TTRALBABL1BCRLMNA | |
| SCHEMBL9244309 | 0.88 | TTR (0.45) | TTRALBABL1BCRLMNA | |
| SCHEMBL1175107 | 0.88 | EGFR (0.54) | TTRALBABL1BCRLMNA | |
| SCHEMBL17744575 | 0.86 | TTR (0.44) | TTRALBABL1BCRLMNA | |
| SCHEMBL8440705 | 0.86 | MEN1 (0.64) | TTRALBLMNAKMT2AMEN1 | |
| SCHEMBL1175171 | 0.86 | CYP19A1 (0.47) | TTRALBLMNAKMT2AMEN1 | |
| SCHEMBL10493540 | 0.86 | NFKB1 (0.45) | TTRALBABL1BCRLMNA | |
| SCHEMBL24190768 | 0.82 | ERN1 (0.60) | LMNAMAPT | |
| SCHEMBL31596359 | 0.82 | PKM (0.49) | TTRALBLMNAPKMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567318-A | Method for synthesizing hydroxybenzonitrile from lignin-based aromatic aldehyde | 南京农业大学 | 2024-02-20 | — | — | CN | claimed |
| EP-2350250-B2 | DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE | DANISCO US INC (US) | 2022-11-30 | — | — | EP | claimed |
| WO-2013173332-A1 | METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN | Vertichem Corporation (CA) | 2013-11-21 | — | — | WO | claimed |
| US-20130232853-A1 | METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN | THESIS CHEMISTRY, LLC (US) | 2013-09-12 | — | — | US | claimed |
| EP-2092113-A2 | LACCASE MEDIATORS AND METHODS OF USE | Danisco US, INC., Genencor Division (US) | 2009-08-26 | — | — | EP | claimed |
| US-20080189871-A1 | LACCASE MEDIATORS AND METHODS OF USE | DANISCO US INC., GENENCOR DIVISION | 2008-08-14 | — | — | US | claimed |
| WO-2008076323-A2 | LACCASE MEDIATORS AND METHODS OF USE | DANISCO US, INC., GENENCOR DIVISION (US) | 2008-06-26 | — | — | WO | claimed |
| US-12195450-B2 | Small molecule neutral sphingomyelinase 2 (nSMase2) inhibitors | THE JOHNS HOPKINS UNIVERSITY (US) | 2025-01-14 | — | — | US | disclosed |
| CN-117567318-A | Method for synthesizing hydroxybenzonitrile from lignin-based aromatic aldehyde | 南京农业大学 | 2024-02-20 | — | — | CN | disclosed |
| EP-2350250-B2 | DELIVERY SYSTEM FOR CO-FORMULATED ENZYME AND SUBSTRATE | DANISCO US INC (US) | 2022-11-30 | — | — | EP | disclosed |
| CN-111825829-B | Triazine ring structure-containing bio-based epoxy resin and preparation method thereof | 大连理工大学 | 2022-05-13 | — | — | CN | disclosed |
| US-20220119374-A1 | SMALL MOLECULE NEUTRAL SPHINGOMYELINASE 2 (nSMase2) INHIBITORS | THE JOHNS HOPKINS UNIVERSITY | 2022-04-21 | — | — | US | disclosed |
| US-20220119374-A1 | SMALL MOLECULE NEUTRAL SPHINGOMYELINASE 2 (nSMase2) INHIBITORS | THE JOHNS HOPKINS UNIVERSITY | 2022-04-21 | — | — | US | disclosed |
| WO-2008076322-A2 | NOVEL LACCASES, COMPOSITIONS AND METHODS OF USE | DANISCO US, INC., GENENCOR DIVISION (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008076323-A2 | LACCASE MEDIATORS AND METHODS OF USE | DANISCO US, INC., GENENCOR DIVISION (US) | 2008-06-26 | — | — | WO | disclosed |
| EP-0566199-B1 | 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | SANOFI SA (FR) | 2000-03-01 | — | — | EP | disclosed |
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0566199-A1 | 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use a s antiviral agents | STERLING WINTHROP INC. (US) | 1993-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195450-B2 | Small molecule neutral sphingomyelinase 2 (nSMase2) inhibitors | SMPD2, SPTLC2, SGMS2 | TTR 4441/4885ALB 3651/4885ABL1 4495/4885 |
| US-20220119374-A1 | SMALL MOLECULE NEUTRAL SPHINGOMYELINASE 2 (nSMase2) INHIBITORS | SMPD2, SPTLC2, SGMS2 | TTR 4441/4885ALB 3651/4885ABL1 4495/4885 |
| US-20130232853-A1 | METHOD FOR SELECTIVE PRODUCTION OF BIOBASED CHEMICALS AND BIOFUELS FROM PLANT LIGNIN | HAAO, HAO2, HACL2 | TTR 2630/4885ALB 1087/4885ABL1 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.