Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 14/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589125 | 0.87 | KCNMA1 (0.81) | KCNMA1KDM4EHIF1AMAPTGAA | |
| SCHEMBL9833874 | 0.83 | CYP1A2 (0.77) | KCNMA1KDM4EMAPTGAAKMT2A | |
| SCHEMBL1308314 | 0.83 | GRIK1 (0.69) | KCNMA1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL13137728 | 0.82 | KCNMA1 (0.72) | KCNMA1KDM4EHIF1AMAPTGAA | |
| SCHEMBL30595248 | 0.81 | RORC (0.67) | KCNMA1MAPTGAAKMT2AMEN1 | |
| SCHEMBL31093979 | 0.81 | KCNMA1 (0.71) | KCNMA1HIF1AMAPTKMT2AMEN1 | |
| SCHEMBL16147455 | 0.81 | KCNMA1 (0.71) | KCNMA1HIF1AMAPTKMT2AMEN1 | |
| SCHEMBL10589176 | 0.81 | RORC (0.67) | KCNMA1MAPTGAAKMT2AMEN1 | |
| SCHEMBL14476825 | 0.81 | KCNMA1 (1.00) | KCNMA1GAAKMT2AMEN1TP53 | |
| SCHEMBL9814400 | 0.80 | CYP1A2 (0.61) | KCNMA1KDM4EMAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004783-A | — | — | None | — | — | JP | disclosed |
| JP-H024783-A | NEW 2-ARYL-BENZOXAZOLE AND NEW 2'-HYDROXYBENZANILIDE | BAYER AG | 1990-01-09 | — | — | JP | disclosed |