Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | METAP2 | P50579 | 1/20 | 0.63 |
| ▸ | RORC | P51449 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122020 | 0.88 | NPC1 (0.67) | CYP1A2CYP2C19HPGDGAANPC1 | |
| SCHEMBL2701801 | 0.86 | HPGD (0.77) | CYP1A2CYP2C19HPGDGAANPC1 | |
| SCHEMBL845142 | 0.85 | LMNA (1.00) | HPGDGAANPC1TP53LMNA | |
| SCHEMBL30595248 | 0.83 | RORC (0.67) | CYP1A2CYP2C19HPGDGAANPC1 | |
| SCHEMBL10589176 | 0.83 | RORC (0.67) | CYP1A2CYP2C19HPGDGAANPC1 | |
| SCHEMBL10337396 | 0.83 | KCNMA1 (0.80) | CYP1A2CYP2C19HPGDGAATP53 | |
| SCHEMBL28842312 | 0.83 | LMNA (0.96) | HPGDGAANPC1TP53LMNA | |
| SCHEMBL28842439 | 0.83 | LMNA (0.96) | HPGDGAANPC1TP53LMNA | |
| SCHEMBL1514283 | 0.82 | HPGD (0.77) | CYP1A2CYP2C19HPGDLMNAHTT | |
| SCHEMBL9621501 | 0.81 | LMNA (0.67) | CYP1A2CYP2C19HPGDGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217149-B1 | POLY(2,2,6,6-TETRAMETHYLPIPERIDYLAMINOSPIROGLYCOLETHER-1,3,5-TRIAZINES) | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1991-01-30 | — | — | EP | disclosed |
| EP-0095031-A2 | N,N,N-tris(2,2,6,6,-tetramethyl-4-piperidone ketal)-1,3,5-triazines and synthetic resin compositions | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1983-11-30 | — | — | EP | disclosed |