Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951744 | 0.80 | MAPT (0.65) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL11528110 | 0.79 | ALDH1A1 (0.65) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL6859623 | 0.79 | ALDH1A1 (0.63) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL17600557 | 0.79 | ALDH1A1 (0.63) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL27986152 | 0.79 | ALDH1A1 (0.63) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL30946935 | 0.79 | ALDH1A1 (0.63) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL30388558 | 0.79 | ALDH1A1 (0.63) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL13541765 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL710469 | 0.77 | ALDH1A1 (0.66) | SMN1; SMN2RAB9ANPC1PDGFRBKDR | |
| SCHEMBL14700162 | 0.77 | DHODH (0.58) | SMN1; SMN2RAB9ANPC1PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011571-A | — | — | None | — | — | JP | disclosed |
| JP-H0211571-A | QUINOLINE COMPOUND AND ITS USE | BASF AG | 1990-01-16 | — | — | JP | disclosed |