SCHEMBL10337667

SCHEMBL10337667

CCc1cc2ccccc2c(O)c1C

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.44
CASP6 P55212 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
NQO1 P15559 1/20 0.41
GPR84 Q9NQS5 1/20 0.41
ATM Q13315 1/20 0.41
ME2 P23368 1/20 0.40
ME1 P48163 1/20 0.40
ME3 Q16798 1/20 0.40
POLB P06746 1/20 0.40
GPR35 Q9HC97 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5704399 0.87 TRPM4 (0.45) TRPM4ME2ME1ME3POLB
SCHEMBL28712363 0.85 GABRA1 (0.42) TRPM4CASP6GABRA1GABRB2GPR84
SCHEMBL1833919 0.85 CASP6 (0.49) TRPM4CASP6GABRA1GABRB2NQO1
SCHEMBL10337577 0.83 TLR8 (0.45) GPR84KDM4E
SCHEMBL2127311 0.82 ATM (0.44) GPR84ATMMEN1KMT2AKDM4E
SCHEMBL8760245 0.82 TYR (0.47) KDM4E
SCHEMBL3957770 0.81 POLB (0.44) TRPM4CASP6GABRA1GABRB2NQO1
SCHEMBL29153179 0.80 TYR (0.50) MEN1KMT2AKDM4E
SCHEMBL11102312 0.80 MEN1 (0.49) TRPM4GABRA1GABRB2POLBMEN1
SCHEMBL16983223 0.79 GPR84 (0.49) TRPM4CASP6GABRA1GABRB2NQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666642-A Resin composition for semiconductor encapsulation and semiconductor device using same SUMITOMO BAKELITE CO 2012-09-12 CN disclosed
US-20120205822-A1 RESIN COMPOSITION FOR ENCAPSULATING SEMICONDUCTOR AND SEMICONDUCTOR DEVICE USING THE RESIN COMPOSITION SUMITOMO BAKELITE CO., LTD. (JP) 2012-08-16 US disclosed
US-4896723-A PHENOLIC RESIN CROSSLINKING MOBIL OIL CORPORATION (US) 1990-01-30 US disclosed
US-4859717-A Cross-linked polyvinyl alcohols and oil reservoir permeability control therewith MOBIL OIL CORPORATION (US) 1989-08-22 US disclosed