Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090850 | 0.92 | PTGS1 (0.54) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL13524349 | 0.81 | PTGS1 (0.65) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL14701620 | 0.80 | PTGS1 (0.64) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL8719438 | 0.79 | PTGS2 (0.68) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL13659014 | 0.78 | PTGS1 (0.61) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL12998566 | 0.78 | PTGS1 (0.61) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL5801365 | 0.78 | PGR (0.50) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL9657535 | 0.77 | PTGS1 (0.60) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL14508943 | 0.77 | SLC22A12 (0.43) | PTGS1PTGS2ADORA3KDM4EMEN1 | |
| SCHEMBL30583076 | 0.77 | PTGS1 (0.60) | PTGS1PTGS2ADORA3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2022260-A | — | — | None | — | — | JP | disclosed |
| JP-H0222260-A | SUBSTITUTED SULFONANILIDE | TAISHO PHARMACEUT CO LTD | 1990-01-25 | — | — | JP | disclosed |