SCHEMBL14701620

SCHEMBL14701620

CS(=O)(=O)Nc1ccc(N)cc1Oc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 9/20 0.64
PTGS2 P35354 7/20 0.64
ADORA3 P0DMS8 2/20 0.64
CYP19A1 P11511 2/20 0.64
KDM4E B2RXH2 1/20 0.64
MEN1 O00255 1/20 0.64
MLNR O43193 1/20 0.64
LMNA P02545 1/20 0.64
MMP1 P03956 1/20 0.64
MPO P05164 1/20 0.64
CYP1A2 P05177 1/20 0.64
GLA P06280 1/20 0.64
CYP3A4 P08684 1/20 0.64
MAPT P10636 1/20 0.64
CYP2C9 P11712 1/20 0.64
HPGD P15428 1/20 0.64
TSHR P16473 1/20 0.64
TBXA2R P21731 1/20 0.64
SLC6A2 P23975 1/20 0.64
APEX1 P27695 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8942128 0.88 PTGS1 (0.55) PTGS1PTGS2ADORA3CYP19A1KDM4E
SCHEMBL13524349 0.84 PTGS1 (0.65) PTGS1PTGS2ADORA3CYP19A1KDM4E
SCHEMBL8719438 0.81 PTGS2 (0.68) PTGS1PTGS2ADORA3CYP19A1KDM4E
SCHEMBL13659014 0.80 PTGS1 (0.61) PTGS1PTGS2ADORA3CYP19A1KDM4E
SCHEMBL10337745 0.80 PTGS1 (0.61) PTGS1PTGS2ADORA3CYP19A1KDM4E
SCHEMBL12998566 0.80 PTGS1 (0.61) PTGS1PTGS2ADORA3CYP19A1KDM4E
SCHEMBL3234161 0.80 LMNA (0.49) PTGS1PTGS2KDM4EMEN1LMNA
Nimesulide SCHEMBL6763666 0.79 CYP19A1 (0.79) PTGS1PTGS2ADORA3CYP19A1KDM4E
SCHEMBL30583076 0.79 PTGS1 (0.60) PTGS1PTGS2ADORA3CYP19A1KDM4E
SCHEMBL9657535 0.79 PTGS1 (0.60) PTGS1PTGS2ADORA3CYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12281133-B2 Hyaluronan conjugate AIHOL CORPORATION (US) 2025-04-22 US disclosed
CN-118773142-A Hybridoma cell strain secreting nimex Shu Lishan clone antibody and application thereof 江南大学 2024-10-15 CN disclosed
CN-115209904-B Hyaluronic acid complex and use of hyaluronic acid complex 爱禾公司 2024-09-10 CN disclosed
EP-4355314-A1 USES OF HYALURONAN CONJUGATE Aihol Corporation (US) 2024-04-24 EP disclosed
CN-116782906-A Use of hyaluronic acid complexes 爱禾公司 2023-09-19 CN disclosed
EP-4217412-A1 WASTE MITIGATION METHODS AND MATERIALS Finite Research Ltd (GB) 2023-08-02 EP disclosed
US-20230227490-A1 HYALURONAN CONJUGATE AIHOL CORPORATION (US) 2023-07-20 US disclosed
US-11643431-B2 Uses of hyaluronan conjugate AIHOL CORPORATION (US) 2023-05-09 US disclosed
EP-4146231-A1 USES OF HYALURONAN CONJUGATE Aihol Corporation (US) 2023-03-15 EP disclosed
WO-2022266472-A1 USES OF HYALURONAN CONJUGATE AIHOL CORPORATION (US) 2022-12-22 WO disclosed
US-20220401567-A1 USES OF HYALURONAN CONJUGATE AIHOL CORPORATION (US) 2022-12-22 US disclosed
CN-115353667-A Method and material for reducing waste 李蓁蓁 2022-11-18 CN disclosed
CN-115209904-A Hyaluronic acid complex and use of hyaluronic acid complex 爱禾公司 2022-10-18 CN disclosed
WO-2022023916-A1 WASTE MITIGATION METHODS AND MATERIALS LI, Zhenzhen (CN) 2022-02-03 WO disclosed
US-20220025119-A1 WASTE MITIGATION METHODS AND MATERIALS LI SHENSHEN (US) 2022-01-27 US disclosed
WO-2021252513-A1 USES OF HYALURONAN CONJUGATE AIHOL CORPORATION (US) 2021-12-16 WO disclosed
US-20210380625-A1 USES OF HYALURONAN CONJUGATE AIHOL CORPORATION (US) 2021-12-09 US disclosed
WO-2013020600-A1 PHARMACEUTICAL COMPOSITION COMPRISING A DRUG CONTAINING AT LEAST ONE TOXICOPHORE FUNCTION AND N-ACETYL-L-CYSTEINE CROSS SA (CH) 2013-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380625-A1 USES OF HYALURONAN CONJUGATE CD44, ENGASE, HEXD PTGS1 1041/4885PTGS2 1851/4885ADORA3 947/4885
US-12281133-B2 Hyaluronan conjugate CD44, HEXD, FUT5 PTGS1 2009/4885PTGS2 2776/4885ADORA3 1445/4885
US-11643431-B2 Uses of hyaluronan conjugate CD44, ENGASE, HEXD PTGS1 1041/4885PTGS2 1851/4885ADORA3 947/4885
US-20220401567-A1 USES OF HYALURONAN CONJUGATE CD44, FUT5, FUT6 PTGS1 2672/4885PTGS2 3226/4885ADORA3 1391/4885
US-20230227490-A1 HYALURONAN CONJUGATE CD44, HEXD, FUT5 PTGS1 2009/4885PTGS2 2776/4885ADORA3 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.