Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.57 |
| ▸ | BAD | Q92934 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421729 | 0.94 | LMNA (0.59) | LMNALTA4HNPC1RXFP1RAB9A | |
| SCHEMBL2892140 | 0.94 | LMNA (0.59) | LMNALTA4HNPC1RXFP1RAB9A | |
| SCHEMBL9355961 | 0.89 | LMNA (0.64) | LMNARXFP1RAB9AMEN1KMT2A | |
| SCHEMBL10629625 | 0.89 | LMNA (0.64) | LMNARXFP1RAB9AMEN1KMT2A | |
| SCHEMBL1864175 | 0.89 | BCL2L1 (0.70) | BCL2L1BADLMNALTA4HNPC1 | |
| SCHEMBL9777084 | 0.89 | BCL2L1 (0.70) | BCL2L1BADLMNALTA4HNPC1 | |
| SCHEMBL9814506 | 0.89 | BCL2L1 (0.70) | BCL2L1BADLMNALTA4HNPC1 | |
| SCHEMBL19604079 | 0.83 | BCL2L1 (0.61) | BCL2L1BADLMNALTA4HNPC1 | |
| SCHEMBL238259 | 0.82 | LTA4H (0.73) | BCL2L1BADLMNALTA4HNPC1 | |
| SCHEMBL12562840 | 0.82 | MAPK1 (0.55) | BCL2L1BADLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000725-A | — | — | None | — | — | JP | disclosed |
| JP-H02725-A | AROMATIC COMPOUNDS | IMPERIAL CHEM IND PLC <ICI> | 1990-01-05 | — | — | JP | disclosed |
| EP-0322151-A2 | Aromatic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-06-28 | — | — | EP | disclosed |