SCHEMBL1864175

SCHEMBL1864175

O=C(c1ccc(F)cc1)c1ccc(-c2ccc(C(=O)c3ccc(F)cc3)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.70
BAD Q92934 1/20 0.70
LTA4H P09960 1/20 0.64
NPC1 O15118 5/20 0.62
RXFP1 Q9HBX9 1/20 0.62
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
PTPN1 P18031 2/20 0.57
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
RAB9A P51151 5/20 0.53
LMNA P02545 4/20 0.53
MAPT P10636 3/20 0.53
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
TP53 P04637 2/20 0.53
HPGD P15428 2/20 0.53
ALPG P10696 1/20 0.53
KDM4E B2RXH2 1/20 0.53
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9777084 1.00 BCL2L1 (0.70) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL9814506 1.00 BCL2L1 (0.70) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL19604079 0.93 BCL2L1 (0.61) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL238259 0.92 LTA4H (0.73) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL8572071 0.92 LTA4H (0.73) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL1736339 0.92 LTA4H (0.73) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL720142 0.91 LMNA (0.67) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL7937415 0.91 LMNA (0.67) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL3296771 0.91 BCL2L1 (0.65) BCL2L1BADLTA4HNPC1RXFP1
SCHEMBL10513615 0.91 LMNA (0.67) BCL2L1BADLTA4HNPC1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874432-B High-temperature-resistant heat-shrinkable material and preparation method thereof 中国科学院长春应用化学研究所 2024-03-26 CN claimed
CN-114874432-A High-temperature-resistant thermal shrinkage material and preparation method thereof 中国科学院长春应用化学研究所 2022-08-09 CN claimed
CN-109081920-A A kind of performed polymer containing sulfoxide structure and preparation method thereof and a kind of advanced composite material 吉林大学 2018-12-25 CN claimed
CN-108948343-A A kind of polymer and preparation method thereof containing sulfoxide radicals 吉林大学 2018-12-07 CN claimed
CN-106008978-A Carboxyl-side-group-containing polyarylether copolymers and preparation method thereof, and application of copolymers in aspect of ultrafiltration membrane hydrophilic modification 吉林大学 2016-10-12 CN claimed
CN-114874432-B High-temperature-resistant heat-shrinkable material and preparation method thereof 中国科学院长春应用化学研究所 2024-03-26 CN disclosed
CN-114874432-B High-temperature-resistant heat-shrinkable material and preparation method thereof 中国科学院长春应用化学研究所 2024-03-26 CN disclosed
CN-117551271-A Polymer and preparation method and application thereof 中国科学院福建物质结构研究所 2024-02-13 CN disclosed
CN-116943456-A Preparation method of hollow fiber membrane and hollow fiber membrane 中国科学院大连化学物理研究所 2023-10-27 CN disclosed
CN-116640298-A Method for preparing benzene end-capped polyaryletherketone by end capping 山东君昊高性能聚合物有限公司 2023-08-25 CN disclosed
CN-114874432-A High-temperature-resistant thermal shrinkage material and preparation method thereof 中国科学院长春应用化学研究所 2022-08-09 CN disclosed
CN-114874432-A High-temperature-resistant thermal shrinkage material and preparation method thereof 中国科学院长春应用化学研究所 2022-08-09 CN disclosed
US-4747988-A Process of making an aromatic polyetherketone fiber product HOECHST CELANESE CORPORATION (US) 1988-05-31 US disclosed
EP-0262919-A2 Preparation of aryl carbonyl compounds RAYCHEM LIMITED (GB) 1988-04-06 EP disclosed
EP-0221149-A1 BLOCK POLYMERS CONTAINING A POLY(ARYL ETHER KETONE) AND METHODS FOR THEIR PRODUCTION AMOCO CORPORATION (US) 1987-05-13 EP disclosed
EP-0202082-A2 Aromatic polyetherketone fiber product and process CELANESE CORPORATION (US) 1986-11-20 EP disclosed
WO-1986006389-A1 BLOCK POLYMERS CONTAINING A POLY(ARYL ETHER KETONE) AND METHODS FOR THEIR PRODUCTION AMOCO CORPORATION (US) 1986-11-06 WO disclosed
EP-0001879-B1 THERMOPLASTIC AROMATIC POLYETHERKETONES, A METHOD FOR THEIR PREPARATION AND THEIR APPLICATION AS ELECTRICAL INSULANTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-03-24 EP disclosed
US-4320224-A Thermoplastic aromatic polyetherketones IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-03-16 US disclosed
EP-0001879-A1 Thermoplastic aromatic polyetherketones, a method for their preparation and their application as electrical insulants IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-05-16 EP disclosed