Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | STK3 | Q13188 | 3/20 | 0.43 |
| ▸ | STK4 | Q13043 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9765063 | 0.98 | RAB9A (0.56) | RAB9AGALR3MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11595017 | 0.95 | RAB9A (0.58) | RAB9AGALR3MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9690935 | 0.88 | RAB9A (0.61) | RAB9AGALR3MAPTKDM4ELMNA | |
| SCHEMBL17815686 | 0.88 | RAB9A (0.60) | RAB9AGALR3MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL17815674 | 0.84 | RAB9A (0.64) | RAB9AGALR3MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL17815682 | 0.83 | RAB9A (0.56) | RAB9AGALR3MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14466445 | 0.82 | GALR3 (0.58) | RAB9AGALR3KDM4ESMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL17802556 | 0.82 | RAB9A (0.55) | RAB9AGALR3MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL21591450 | 0.79 | RAB9A (0.52) | RAB9AGALR3MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4057859 | 0.78 | GALR3 (0.61) | RAB9AGALR3MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355085-A1 | A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES. | CO PHARMA CORP SRL (IT) | 1990-02-28 | — | — | EP | disclosed |
| WO-1988005437-A1 | A PROCESS FOR THE PREPARATION OF 9-(HYDROXYALKYL)-HYPOXANTHINES | CO PHARMA CORPORATION S.R.L. (IT) | 1988-07-28 | — | — | WO | disclosed |
| US-4100286-A | 2-(Substituted heterocyclic amine)benzoic acids | SCIENCE UNION ET CIE (FR) | 1978-07-11 | — | — | US | disclosed |