Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595017 | 0.90 | RAB9A (0.58) | RAB9AGALR3KDM4CMAPTLMNA | |
| SCHEMBL17815674 | 0.89 | RAB9A (0.64) | RAB9AGALR3KDM4CMAPTLMNA | |
| SCHEMBL10338024 | 0.88 | RAB9A (0.57) | RAB9AGALR3KDM4CMAPTLMNA | |
| Hydrochloric Acid SCHEMBL9765063 | 0.87 | RAB9A (0.56) | RAB9AGALR3KDM4CMAPTLMNA | |
| SCHEMBL17815686 | 0.85 | RAB9A (0.60) | RAB9AGALR3KDM4CMAPTLMNA | |
| SCHEMBL4057859 | 0.82 | GALR3 (0.61) | RAB9AGALR3KDM4CMAPTLMNA | |
| SCHEMBL17815682 | 0.81 | RAB9A (0.56) | RAB9AGALR3KDM4CMAPTLMNA | |
| SCHEMBL19980064 | 0.80 | RAB9A (0.56) | RAB9AGALR3KDM4CMAPTLMNA | |
| Hydrochloric Acid SCHEMBL17802556 | 0.79 | RAB9A (0.55) | RAB9AGALR3KDM4CMAPTLMNA | |
| SCHEMBL14466445 | 0.79 | GALR3 (0.58) | RAB9AGALR3KDM4CLMNACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294074-B1 | DIHYDROPYRIDINE ANTI-ALLERGIC AND ANTI-INFLAMMATORY AGENTS | Pfizer Limited (GB) | 1992-04-08 | — | — | EP | disclosed |
| US-4851412-A | ASTHMA, ARTHRITIS | PFIZER INC. (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0294074-A1 | Dihydropyridine anti-allergic and anti-inflammatory agents | Pfizer Limited (GB) | 1988-12-07 | — | — | EP | disclosed |
| US-4100286-A | 2-(Substituted heterocyclic amine)benzoic acids | SCIENCE UNION ET CIE (FR) | 1978-07-11 | — | — | US | disclosed |