Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | GALR3 | O60755 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | STK3 | Q13188 | 3/20 | 0.46 |
| ▸ | PLK4 | O00444 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | ROS1 | P08922 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | MARK3 | P27448 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338024 | 0.95 | RAB9A (0.57) | RAB9AGALR3CYP1A2NPC1KDM4C | |
| Hydrochloric Acid SCHEMBL9765063 | 0.94 | RAB9A (0.56) | RAB9AGALR3CYP1A2NPC1KDM4C | |
| SCHEMBL9690935 | 0.90 | RAB9A (0.61) | RAB9AGALR3CYP1A2KDM4CCDK1 | |
| SCHEMBL17815686 | 0.90 | RAB9A (0.60) | RAB9AGALR3CYP1A2NPC1KDM4C | |
| SCHEMBL17815674 | 0.86 | RAB9A (0.64) | RAB9AGALR3CYP1A2NPC1KDM4C | |
| SCHEMBL17815682 | 0.85 | RAB9A (0.56) | RAB9AGALR3CYP1A2KDM4CSTK17A | |
| SCHEMBL14466445 | 0.83 | GALR3 (0.58) | RAB9AGALR3NPC1KDM4CCDK1 | |
| Hydrochloric Acid SCHEMBL17802556 | 0.83 | RAB9A (0.55) | RAB9AGALR3CYP1A2KDM4CSTK17A | |
| SCHEMBL21591450 | 0.80 | RAB9A (0.52) | RAB9AGALR3CYP1A2NPC1KDM4C | |
| SCHEMBL4057859 | 0.79 | GALR3 (0.61) | RAB9AGALR3NPC1KDM4CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075572-A2 | ORALLY ACTIVE PURINE-BASED INHIBITORS OF HEAT SHOCK PROTEIN 90 | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20070129334-A1 | Orally Active Purine-Based Inhibitors of Heat Shock Protein 90 | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-06-07 | — | — | US | disclosed |
| US-20070129334-A1 | Orally Active Purine-Based Inhibitors of Heat Shock Protein 90 | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-06-07 | — | — | US | disclosed |
| US-4100286-A | 2-(Substituted heterocyclic amine)benzoic acids | SCIENCE UNION ET CIE (FR) | 1978-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129334-A1 | Orally Active Purine-Based Inhibitors of Heat Shock Protein 90 | HSP90AB1, HSP90AA1, HSP90AB2P | RAB9A 2657/4885GALR3 4776/4885CYP1A2 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.