Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726529 | 0.79 | CYP3A4 (0.41) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11450210 | 0.76 | SMN1; SMN2 (0.38) | ALDH1A1POLBGAACDC25ASMN1; SMN2 | |
| SCHEMBL8726512 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19035696 | 0.75 | CNR2 (0.43) | ALDH1A1MAPTPOLBCNR2CNR1 | |
| SCHEMBL11459127 | 0.74 | LMNA (0.71) | ALDH1A1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL8726366 | 0.71 | PLA2G10 (0.56) | ALDH1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL11265232 | 0.70 | PLA2G10 (0.48) | ALDH1A1POLBGAAMMP1MMP3 | |
| SCHEMBL11842998 | 0.70 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12706790 | 0.69 | KMT2A (0.53) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL22265963 | 0.69 | LMNA (0.68) | ALDH1A1CYP1A2CYP2C9CYP2C19CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H0219363-A | IMIDAZOLIDINE DERIVATIVE | FUJISAWA PHARMACEUT CO LTD | 1990-01-23 | — | — | JP | disclosed |
| JP-2019363-A | — | — | 0001-01-01 | — | — | JP | disclosed |