Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726366 | 0.92 | PLA2G10 (0.56) | PLA2G10PLA2G5MMP1MMP3MMP9 | |
| SCHEMBL11271882 | 0.86 | PLA2G10 (0.53) | PLA2G10PLA2G5MMP1MMP3MMP9 | |
| SCHEMBL11267916 | 0.84 | CAPN1 (0.48) | PLA2G10PLA2G5MMP1MMP3MMP9 | |
| SCHEMBL11256499 | 0.84 | NPSR1 (0.49) | PLA2G10PLA2G5MMP1MMP3MMP9 | |
| SCHEMBL11263507 | 0.84 | LMNA (0.47) | PLA2G10PLA2G5MMP1MMP3MMP9 | |
| SCHEMBL11271655 | 0.83 | HDAC1 (0.51) | PLA2G10PLA2G5MMP1MMP3MMP9 | |
| SCHEMBL11264004 | 0.83 | MMP1 (0.40) | PLA2G10PLA2G5MMP1MMP3MMP9 | |
| SCHEMBL11270328 | 0.82 | POLB (0.47) | MMP1MMP3MMP9POLBALOX15 | |
| SCHEMBL11266748 | 0.82 | L3MBTL1 (0.42) | PLA2G10PLA2G5MMP1MMP3MMP9 | |
| SCHEMBL11263373 | 0.81 | KMT2A (0.52) | PLA2G10PLA2G5MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005647-B1 | HYDANTOIN COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | Lilly Industries Limited (GB) | 1982-06-09 | — | — | EP | disclosed |
| US-4293563-A | ANTIASTHMATICS | LILLY INDUSTRIES LIMITED (GB) | 1981-10-06 | — | — | US | disclosed |
| US-4241073-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1980-12-23 | — | — | US | disclosed |
| EP-0005647-A1 | Hydantoin compounds, their preparation and pharmaceutical formulations containing them | Lilly Industries Limited (GB) | 1979-11-28 | — | — | EP | disclosed |