SCHEMBL1033833

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034526	0.87	SIRT5 (0.49)	RAB9ANPC1KDM4EMAPTMAPK1
	SCHEMBL1032901	0.86	NPC1 (0.50)	RAB9ANPC1KDM4ELMNAHSD17B10
	SCHEMBL17772349	0.85	SIRT5 (0.45)	RAB9ANPC1KDM4EMAPTMAPK1
	SCHEMBL12673386	0.84	PARP1 (0.54)	RAB9ASMN1; SMN2NPC1HSP90AA1KDM4E
	SCHEMBL1031016	0.82	USP2 (0.56)	RAB9ASMN1; SMN2NPC1KDM4EMAPT
	SCHEMBL3608132	0.80	SMN1; SMN2 (0.71)	RAB9ASMN1; SMN2NPC1HSP90AA1KDM4E
	SCHEMBL1034416	0.79	KMT2A (0.48)	RAB9ASMN1; SMN2NPC1KDM4ETDP1
	SCHEMBL1034840	0.79	SMN1; SMN2 (0.59)	RAB9ASMN1; SMN2NPC1KDM4ETDP1
	SCHEMBL1031845	0.78	ALDH1A1 (0.45)	RAB9ASMN1; SMN2NPC1KDM4EMAPT
	SCHEMBL1034835	0.78	SIRT2 (0.51)	RAB9ASMN1; SMN2NPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.