SCHEMBL10338385

SCHEMBL10338385

Cc1ccccc1S(=O)(=O)CC(=O)O.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.50
MMP2 P08253 1/20 0.49
MMP7 P09237 1/20 0.49
MMP14 P50281 1/20 0.49
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
ALDH1A1 P00352 1/20 0.44
ALOX12 P18054 1/20 0.44
HTT P42858 1/20 0.44
HSD11B1 P28845 2/20 0.43
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2068996 0.98 FFAR1 (0.51) FFAR1MMP2MMP7MMP14CA12
SCHEMBL28541962 0.84 CA12 (0.49) FFAR1MMP2MMP7MMP14CA12
SCHEMBL581476 0.83 ALDH1A1 (0.46) ALDH1A1ALOX12HTTHSD11B1KEAP1
SCHEMBL5320032 0.82 RECQL (0.61) ALDH1A1HSD11B1KMT2AMEN1ITGAV
SCHEMBL4924795 0.81 ALDH1A1 (0.53) CA1CA2CA9ALDH1A1ALOX12
Hydrazine SCHEMBL28015266 0.80 ALDH1A1 (0.43) CA12CA1CA2CA9ALDH1A1
SCHEMBL10514057 0.80 APEX1 (0.64) ALDH1A1ALOX12HTTHSD11B1KEAP1
SCHEMBL10581834 0.79 MMP2 (0.50) FFAR1MMP2MMP7MMP14CA12
SCHEMBL28922109 0.78 CA12 (0.52) CA12CA1CA2CA9ALDH1A1
SCHEMBL17783669 0.78 ALDH1A1 (0.46) ALDH1A1ALOX12HTTHSD11B1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2069452-A None JP disclosed
JP-H0269452-A PRODUCTION OF DIIODIDOMETHYL-P-TOLYLSULFONE MITSUI TOATSU CHEM INC 1990-03-08 JP disclosed