SCHEMBL581476

SCHEMBL581476

CC(=O)CS(=O)(=O)c1ccccc1C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
ALOX12 P18054 1/20 0.46
HTT P42858 1/20 0.46
POLB P06746 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
HCRTR2 O43614 1/20 0.41
GAA P10253 1/20 0.41
HSD11B1 P28845 1/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
THRB P10828 1/20 0.39
RAPGEF4 Q8WZA2 1/20 0.39
KAT6A Q92794 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL28015266 0.96 ALDH1A1 (0.43) ALDH1A1ALOX12HTTPOLBSMN1; SMN2
SCHEMBL2068996 0.85 FFAR1 (0.51) ALDH1A1ALOX12HTTPOLBKEAP1
SCHEMBL10338385 0.83 FFAR1 (0.50) ALDH1A1ALOX12HTTPOLBKEAP1
SCHEMBL4924795 0.83 ALDH1A1 (0.53) ALDH1A1ALOX12HTTPOLBKEAP1
SCHEMBL17783669 0.83 ALDH1A1 (0.46) ALDH1A1ALOX12HTTPOLBKEAP1
SCHEMBL6911920 0.81 ALDH1A1 (0.54) ALDH1A1ALOX12HTTPOLBKEAP1
SCHEMBL18191553 0.80 POLB (0.45) ALDH1A1ALOX12HTTPOLBKEAP1
SCHEMBL5320032 0.80 RECQL (0.61) ALDH1A1SMN1; SMN2HSD11B1KMT2AMEN1
SCHEMBL10872137 0.79 ALDH1A1 (0.43) ALDH1A1POLBSMN1; SMN2GAAHSD11B1
SCHEMBL11692985 0.78 KEAP1 (0.46) ALDH1A1ALOX12HTTPOLBKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1758833-B1 IMPROVING THE FREEZE-THAW DURABILITY OF DRY CAST CEMENTITIOUS MIXTURES CONSTR RES & TECH GMBH (DE) 2016-06-01 EP claimed
EP-1758836-B1 PROVIDING FREEZING AND THAWING RESISTANCE TO CEMENTITIOUS COMPOSITIONS CONSTR RES & TECH GMBH (DE) 2013-08-14 EP claimed
US-7922808-B2 Freeze-thaw durability of dry cast cementitious mixtures CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2011-04-12 US claimed
CN-1980869-B Cement casting compositions and its preparation method CONSTR RES & TECH GMBH 2010-10-06 CN claimed
US-7435766-B2 Method of delivery of agents providing freezing and thawing resistance to cementitious compositions CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2008-10-14 US claimed
CN-101198567-A Method of delivery of agents providing freezing and thawing resistance to cementitious compositions CONSTR RES & TECH GMBH (DE) 2008-06-11 CN claimed
EP-1893551-A2 METHOD OF DELIVERY OF AGENTS PROVIDING FREEZING AND THAWING RESISTANCE TO CEMENTITIOUS COMPOSITIONS Construction Research & Technology GmbH (DE) 2008-03-05 EP claimed
WO-2008009395-A1 EXPANDABLE CROSS-LINKED POLYETHYLENE, METHOD FOR MANUFACTURING IT, AND APPARATUS FOR PERFORMING THE METHOD MASTERPLAST S.R.L. (IT) 2008-01-24 WO claimed
US-7288147-B2 Providing freezing and thawing resistance to cementitious compositions CONSTRUCTION RESEARCH&TECHNOLOGY GMBH (DE) 2007-10-30 US claimed
CN-1980869-A Providing freezing and thawing resistance to cementitious compositions CONSTR RES & TECH GMBH (DE) 2007-06-13 CN claimed
EP-1758833-A2 IMPROVING THE FREEZE-THAW DURABILITY OF DRY CAST CEMENTITIOUS MIXTURES DIE Construction Research & Technology GmbH (DE) 2007-03-07 EP claimed
EP-1758836-A2 PROVIDING FREEZING AND THAWING RESISTANCE TO CEMENTITIOUS COMPOSITIONS DIE Construction Research & Technology GmbH (DE) 2007-03-07 EP claimed
WO-2006133855-A2 METHOD OF DELIVERY OF AGENTS PROVIDING FREEZING AND THAWING RESISTANCE TO CEMENTITIOUS COMPOSITIONS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2006-12-21 WO claimed
US-20060281835-A1 Method of delivery of agents providing freezing and thawing resistance to cementitious compositions CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2006-12-14 US claimed
WO-2005123624-A2 PROVIDING FREEZING AND THAWING RESISTANCE TO CEMENTITIOUS COMPOSITIONS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-12-29 WO claimed
WO-2005123619-A2 IMPROVING THE FREEZE-THAW DURABILITY OF DRY CAST CEMENTITIOUS MIXTURES CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-12-29 WO claimed
US-20050274294-A1 Freeze-thaw durability of dry cast cementitious mixtures CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-12-15 US claimed
US-20050274285-A1 Providing freezing and thawing resistance to cementitious compositions CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-12-15 US claimed
JP-2024327-A None JP disclosed
JP-H00224327-A 0001-01-01 JP disclosed