Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30285975 | 1.00 | CCR1 (0.54) | CCR1KCNH2NOS2PDE10ARAB9A | |
| SCHEMBL30459407 | 1.00 | CCR1 (0.54) | CCR1KCNH2NOS2PDE10ARAB9A | |
| SCHEMBL10338656 | 0.98 | KCNH2 (0.55) | CCR1KCNH2NOS2PDE10ARAB9A | |
| SCHEMBL22200840 | 0.96 | CCR1 (0.50) | CCR1KCNH2NOS2PDE10ARAB9A | |
| SCHEMBL30459461 | 0.93 | KCNH2 (0.61) | CCR1KCNH2NOS2PDE10AESR1 | |
| SCHEMBL29028490 | 0.93 | KCNH2 (0.61) | CCR1KCNH2NOS2PDE10AESR1 | |
| SCHEMBL25438253 | 0.91 | KCNH2 (0.59) | CCR1KCNH2NOS2PDE10AESR1 | |
| SCHEMBL31026592 | 0.91 | KCNH2 (0.64) | CCR1KCNH2ESR1LTB4R | |
| SCHEMBL10531797 | 0.91 | KCNH2 (0.64) | CCR1KCNH2ESR1LTB4R | |
| SCHEMBL10511946 | 0.91 | KCNH2 (0.64) | CCR1KCNH2ESR1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105374949-A | Organic light-emitting device and preparation method thereof | UNIV ELECTRONIC SCIENCE & TECH CHINA | 2016-03-02 | — | — | CN | claimed |
| CN-104003828-B | The preparation method of copper complex catalytic amine and aromatic nitriles linked reaction under visible light | TIANJIN NORMAL UNIVERSITY (CN) | 2015-08-19 | — | — | CN | claimed |
| US-20150125550-A1 | APPLICATION OF 2,9-DI-SEC-BUTYL-1,10-PHENANTHROLINE AS A GLIOBLASTOMA TUMOR CHEMOTHERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-05-07 | — | — | US | claimed |
| US-7238832-B2 | Production method of a coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-07-03 | — | — | US | claimed |
| EP-1449580-B1 | Production method of a cross-coupling compound from an alkyl halide and an organoboron compound | SUMITOMO CHEMICAL CO (JP) | 2005-12-28 | — | — | EP | claimed |
| US-20040167364-A1 | Production method of a coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-26 | — | — | US | claimed |
| EP-1449580-A1 | Production method of a cross-coupling compound from an alkyl halide and an organoboron compound | Sumitomo Chemical Co.,Ltd. (JP) | 2004-08-25 | — | — | EP | claimed |
| EP-0853064-B1 | Process for the synthesis of hydrogen peroxide | ENICHEM SPA (IT) | 2000-02-23 | — | — | EP | claimed |
| EP-0808796-B1 | Process for the preparation of hydrogen peroxide | ENICHEM SPA (IT) | 2000-02-09 | — | — | EP | claimed |
| EP-0894783-A1 | Process for the synthesis of phenol from benzene | Enichem S.p.A. (IT) | 1999-02-03 | — | — | EP | claimed |
| US-5783164-A | PALLADIUM CATALYST WITH A NITROGENATED LIGAND STABLE TO OXIDATION | ENICHEM S.P.A. (IT) | 1998-07-21 | — | — | US | claimed |
| EP-0853064-A1 | Process for the synthesis of hydrogen peroxide | ENICHEM S.p.A. (IT) | 1998-07-15 | — | — | EP | claimed |
| EP-0808796-A1 | Process for the preparation of hydrogen peroxide | ENICHEM S.p.A. (IT) | 1997-11-26 | — | — | EP | claimed |
| EP-0628805-B1 | Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution | AVL MEDICAL INSTR AG (CH) | 1996-09-18 | — | — | EP | claimed |
| US-5464587-A | In blood | AVL MEDICAL INSTRUMENTS AG (CH) | 1995-11-07 | — | — | US | claimed |
| EP-0628805-A1 | Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution | AVL Medical Instruments AG (CH) | 1994-12-14 | — | — | EP | claimed |
| US-4861455-A | Electrode membrane | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1989-08-29 | — | — | US | claimed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| US-4861455-A | Electrode membrane | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1989-08-29 | — | — | US | disclosed |
| US-4853090-A | Lithium ion-selective compositions, electrodes and a method of use | EASTMAN KODAK COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167364-A1 | Production method of a coupling compound | PYM1, BRIX1, CXCR1 | CCR1 94/4885KCNH2 362/4885NOS2 391/4885 |
| US-20150125550-A1 | APPLICATION OF 2,9-DI-SEC-BUTYL-1,10-PHENANTHROLINE AS A GLIOBLASTOMA TUMOR CHEMOTHERAPY | TOE1, SCLY, SUB1 | CCR1 3808/4885KCNH2 3099/4885NOS2 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.