SCHEMBL22200840

SCHEMBL22200840

CCCCc1ccc2ccc3ccc(CCC)nc3c2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.50
KCNH2 Q12809 1/20 0.48
NOS2 P35228 2/20 0.39
PDE10A Q9Y233 1/20 0.38
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
RAB9A P51151 1/20 0.34
CCR5 P51681 1/20 0.34
HSD17B10 Q99714 2/20 0.34
PARP1 P09874 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HRH2 P25021 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
TLR7 Q9NYK1 2/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
XBP1 P17861 1/20 0.34
HTT P42858 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30459407 0.96 CCR1 (0.54) CCR1KCNH2NOS2PDE10AESR1
SCHEMBL432244 0.96 CCR1 (0.54) CCR1KCNH2NOS2PDE10AESR1
SCHEMBL30285975 0.96 CCR1 (0.54) CCR1KCNH2NOS2PDE10AESR1
SCHEMBL10338656 0.94 KCNH2 (0.55) CCR1KCNH2NOS2PDE10AESR1
SCHEMBL29028490 0.89 KCNH2 (0.61) CCR1KCNH2NOS2PDE10AESR1
SCHEMBL30459461 0.89 KCNH2 (0.61) CCR1KCNH2NOS2PDE10AESR1
SCHEMBL25438253 0.88 KCNH2 (0.59) CCR1KCNH2NOS2PDE10AESR1
SCHEMBL10531797 0.88 KCNH2 (0.64) CCR1KCNH2ESR1HSD17B10KDM4E
SCHEMBL31026592 0.88 KCNH2 (0.64) CCR1KCNH2ESR1HSD17B10KDM4E
SCHEMBL10511946 0.88 KCNH2 (0.64) CCR1KCNH2ESR1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3677612-A1 HIGH PERFORMANCE PHOTOINITIATING SYSTEMS FOR POLYMER/OPAQUE FILLER COMPOSITES Université de Haute Alsace (FR) 2020-07-08 EP disclosed