Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339183 | 0.79 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2STAT1KMT2A | |
| SCHEMBL9332054 | 0.77 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2STAT1KMT2A | |
| SCHEMBL7688372 | 0.76 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2STAT1KMT2A | |
| SCHEMBL3652897 | 0.74 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2STAT1KMT2A | |
| SCHEMBL10339209 | 0.72 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2STAT1KMT2A | |
| SCHEMBL15525568 | 0.70 | KMT2A (0.58) | NPC1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL15525567 | 0.70 | KMT2A (0.58) | NPC1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL6154147 | 0.67 | RBBP9 (0.49) | NPC1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL6142534 | 0.67 | RBBP9 (0.46) | NPC1RAB9ASMN1; SMN2STAT1KMT2A | |
| SCHEMBL6142531 | 0.67 | RBBP9 (0.46) | NPC1RAB9ASMN1; SMN2STAT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2169583-A | — | — | None | — | — | JP | disclosed |
| JP-H02169583-A | VINYLTHIAZOLE DERIVATIVE AND DRUG CONTAINING SAME DERIVATIVE AS ACTIVE INGREDIENT | MITSUBISHI KASEI CORP | 1990-06-29 | — | — | JP | disclosed |