SCHEMBL7688372

SCHEMBL7688372

N#CC(=Cc1ccccc1)c1nccs1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
POLB P06746 1/20 0.56
PKM P14618 1/20 0.56
FTO Q9C0B1 1/20 0.52
MAPT P10636 7/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 2/20 0.47
LMNA P02545 2/20 0.47
RECQL P46063 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TP53 P04637 2/20 0.46
EGFR P00533 1/20 0.46
IGF1R P08069 1/20 0.46
IGF2R P11717 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
JAK3 P52333 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29611513 0.85 MAPT (0.48) NPC1RAB9APOLBPKMFTO
SCHEMBL16532962 0.79 FTO (0.47) NPC1RAB9APOLBPKMFTO
SCHEMBL10339209 0.78 NPC1 (0.40) NPC1RAB9APOLBPKMFTO
SCHEMBL16533076 0.76 ALDH1A1 (0.47) NPC1RAB9APOLBPKMFTO
SCHEMBL10339149 0.76 NPC1 (0.46) NPC1RAB9APOLBPKMMEN1
SCHEMBL10339183 0.76 NPC1 (0.46) NPC1RAB9APOLBPKMMEN1
SCHEMBL7535989 0.75 FTO (0.45) NPC1RAB9APOLBPKMFTO
SCHEMBL16532974 0.75 FTO (0.44) NPC1RAB9APOLBFTOMAPT
SCHEMBL27963933 0.74 FTO (0.43) NPC1RAB9APOLBPKMFTO
SCHEMBL16532988 0.74 FTO (0.43) NPC1RAB9APOLBFTOMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110573496-A N- (4-pyridyl) nicotinamide compounds or salts thereof 石原产业株式会社 2019-12-13 CN disclosed
CN-105123695-A Control agent for soft rot and control method for the same ISHIHARA SANGYO KAISHA 2015-12-09 CN disclosed
CN-105142401-A Pest control agent ISHIHARA SANGYO KAISHA 2015-12-09 CN disclosed
CN-103118539-B Soft rot control agent and soft rot control method Ishihara Sangyo Kabushiki Kaisha Ltd. (JP) 2015-09-16 CN disclosed
CN-104837344-A Oil-based pesticidal suspension ISHIHARA SANGYO KAISHA 2015-08-12 CN disclosed
CN-102123589-B Method for controlling degradation of agrochemical active ingredients ISHIHARA SANGYO KAISHA 2015-03-25 CN disclosed
CN-101980605-B Bactericide composition for agriculture and horticulture and method for preventing plant diseases ISHIHARA SANGYO KAISHA 2014-12-03 CN disclosed
CN-102802422-B Agent for controlling soft rot and method for controlling the same ISHIHARA SANGYO KAISHA 2014-12-03 CN disclosed
CN-103140135-B Copulation disruption agent for sap-sucking pests ISHIHARA SANGYO KAISHA 2014-07-23 CN disclosed
CN-103833667-A Phenyl thiazolyl acrylonitrile compound and application thereof SINOCHEM CORP 2014-06-04 CN disclosed
CN-102802422-A Agent for controlling soft rot and method for controlling the same ISHIHARA SANGYO KAISHA 2012-11-28 CN disclosed
CN-102123589-A Method for controlling degradation of agrochemical active ingredients ISHIHARA SANGYO KAISHA 2011-07-13 CN disclosed
CN-101980605-A Bactericide composition for agriculture and horticulture and method for preventing plant diseases ISHIHARA SANGYO KAISHA 2011-02-23 CN disclosed
CN-1162412-C Thiazolylcinnamonitriles and pest controlling agents �ձ�������ʽ���� 2004-08-18 CN disclosed
CN-1413201-A Thiazolylcinnamonitrile compounds and insecticides and miticides NIPPON SODA CO (JP) 2003-04-23 CN disclosed
US-6492404-B1 EFFICACIOUS, SAFE NIPPON SODA CO., LTD. (JP) 2002-12-10 US disclosed
US-6492404-B1 EFFICACIOUS, SAFE NIPPON SODA CO., LTD. (JP) 2002-12-10 US disclosed
CN-1318061-A Thiazolylcinnamonitriles and pest controlling agents NIPPON SODA CO (JP) 2001-10-17 CN disclosed
JP-2001261665-A THIAZOLYLCINNAMIC ACID NITRILE COMPOUND AND HARMFUL ORGANISM CONTROLLING AGENT NIPPON SODA CO LTD 2001-09-26 JP disclosed
EP-1114820-A1 THIAZOLYLCINNAMONITRILES AND PEST CONTROLLING AGENTS NIPPON SODA CO., LTD. (JP) 2001-07-11 EP disclosed