Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBBP9 | O75884 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529933 | 0.78 | RBBP9 (0.48) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| SCHEMBL2008703 | 0.78 | PLA2G7 (0.57) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| SCHEMBL6154144 | 0.78 | RBBP9 (0.48) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| Bromide SCHEMBL27504054 | 0.77 | PLA2G7 (0.56) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| SCHEMBL2009037 | 0.76 | RBBP9 (0.49) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| SCHEMBL2009038 | 0.76 | RBBP9 (0.49) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| SCHEMBL6142531 | 0.76 | RBBP9 (0.46) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| SCHEMBL6142534 | 0.76 | RBBP9 (0.46) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| SCHEMBL5610849 | 0.74 | RBBP9 (0.44) | RBBP9NPC1RAB9APLA2G4AALDH1A1 | |
| SCHEMBL9346822 | 0.73 | PLA2G4A (0.49) | RBBP9NPC1RAB9APLA2G4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103180-B1 | Hydroxyphenylvinylthizoles | CIBA SC HOLDING AG (CH) | 2005-01-12 | — | — | EP | claimed |