Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 1/20 | 0.76 |
| ▸ | APP | P05067 | 10/20 | 0.76 |
| ▸ | MAT2A | P31153 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CASP1 | P29466 | 2/20 | 0.59 |
| ▸ | HBB | P68871 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339261 | 1.00 | RELA (0.76) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL2773826 | 0.92 | APP (0.71) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL2773829 | 0.92 | APP (0.71) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL14387613 | 0.88 | APP (0.67) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL11895254 | 0.87 | NFE2L2 (0.67) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL13264675 | 0.87 | APP (0.65) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL2945333 | 0.87 | APP (1.00) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL2945337 | 0.87 | APP (1.00) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL11895252 | 0.87 | NFE2L2 (0.67) | RELAAPPMAT2AKCNH2PTGS1 | |
| SCHEMBL29404131 | 0.87 | NFE2L2 (0.67) | RELAAPPMAT2AKCNH2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2187734-A | — | — | None | — | — | JP | disclosed |
| JP-H02187734-A | NONLINEAR OPTICAL ORGANIC MATERIAL | SEKISUI CHEM CO LTD | 1990-07-23 | — | — | JP | disclosed |