Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 9/20 | 0.71 |
| ▸ | RELA | Q04206 | 1/20 | 0.70 |
| ▸ | MAT2A | P31153 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | HBB | P68871 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773826 | 1.00 | APP (0.71) | APPRELAMAT2AKCNH2PTGS1 | |
| SCHEMBL10339262 | 0.92 | RELA (0.76) | APPRELAMAT2AKCNH2PTGS1 | |
| SCHEMBL10339261 | 0.92 | RELA (0.76) | APPRELAMAT2AKCNH2PTGS1 | |
| SCHEMBL2775532 | 0.90 | RELA (0.67) | APPRELAMAT2AKCNH2PTGS1 | |
| SCHEMBL2775527 | 0.90 | RELA (0.67) | APPRELAMAT2AKCNH2PTGS1 | |
| SCHEMBL13264738 | 0.87 | APP (0.67) | APPRELAPTGS1NQO2ALDH1A1 | |
| SCHEMBL14387613 | 0.85 | APP (0.67) | APPRELAMAT2AKCNH2PTGS1 | |
| SCHEMBL13264714 | 0.84 | CYP1A1 (0.58) | APPRELAMAT2AKCNH2PTGS1 | |
| SCHEMBL13264720 | 0.84 | RELA (0.67) | APPRELANQO2TUBB4ATUBB | |
| SCHEMBL11895254 | 0.83 | NFE2L2 (0.67) | APPRELAMAT2AKCNH2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100302927-A1 | OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2010-12-02 | — | — | US | disclosed |