Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.46 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340083 | 1.00 | SSTR3 (0.48) | SSTR3TDP1NPC1RAB9AMCOLN2 | |
| Hydrochloric Acid SCHEMBL10340356 | 0.98 | SSTR3 (0.47) | SSTR3TDP1NPC1RAB9AMCOLN2 | |
| Hydrochloric Acid SCHEMBL10340355 | 0.98 | SSTR3 (0.47) | SSTR3TDP1NPC1RAB9AMCOLN2 | |
| SCHEMBL17211643 | 0.87 | SSTR3 (0.46) | SSTR3TDP1NPC1RAB9AMCOLN2 | |
| SCHEMBL11472624 | 0.87 | RAB9A (0.59) | SSTR3NPC1RAB9AMLYCDSMN1; SMN2 | |
| SCHEMBL11472627 | 0.87 | RAB9A (0.59) | SSTR3NPC1RAB9AMLYCDSMN1; SMN2 | |
| SCHEMBL11465350 | 0.85 | F10 (0.52) | NPC1RAB9AMLYCDTAS1R3TAS1R1 | |
| Bromadoline SCHEMBL1817293 | 0.85 | MLYCD (0.46) | SSTR3NPC1RAB9AMLYCDSMN1; SMN2 | |
| SCHEMBL11464453 | 0.85 | SSTR3 (0.58) | SSTR3NPC1RAB9AMLYCDTAS1R3 | |
| Bromadoline SCHEMBL10697265 | 0.85 | MLYCD (0.46) | SSTR3NPC1RAB9AMLYCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248824-B1 | USE OF CIS-N-(2 AMINOCYCLOALIPHATIC) BENZENE ACETAMIDE AND BENZAMIDE FOR THE MANUFACTURE OF ANTICONVULSANTS | THE UPJOHN COMPANY (US) | 1990-01-17 | — | — | EP | claimed |
| EP-0248824-A1 | Use of CIS-N-(2 Aminocycloaliphatic) benzene acetamide and Benzamide for the manufacture of anticonvulsants. | UPJOHN CO (US) | 1987-12-16 | — | — | EP | claimed |
| EP-0222533-A1 | Cis-N-[(2-aminocycloaliphatic)benzene acetamide and -benzamide anticonvulsants | THE UPJOHN COMPANY (US) | 1987-05-20 | — | — | EP | claimed |
| WO-1987002584-A1 | CIS-N-(2-AMINOCYCLOALIPHATIC)BENZENE ACETAMIDE AND -BENZAMIDE ANTICONVULSANTS | THE UPJOHN COMPANY (US) | 1987-05-07 | — | — | WO | claimed |
| EP-0248824-B1 | USE OF CIS-N-(2 AMINOCYCLOALIPHATIC) BENZENE ACETAMIDE AND BENZAMIDE FOR THE MANUFACTURE OF ANTICONVULSANTS | THE UPJOHN COMPANY (US) | 1990-01-17 | — | — | EP | disclosed |
| US-4801604-A | REDUCED ANALGESIC PROPERTIES | THE UPJOHN COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0248824-A1 | Use of CIS-N-(2 Aminocycloaliphatic) benzene acetamide and Benzamide for the manufacture of anticonvulsants. | UPJOHN CO (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0222533-A1 | Cis-N-[(2-aminocycloaliphatic)benzene acetamide and -benzamide anticonvulsants | THE UPJOHN COMPANY (US) | 1987-05-20 | — | — | EP | disclosed |
| WO-1987002584-A1 | CIS-N-(2-AMINOCYCLOALIPHATIC)BENZENE ACETAMIDE AND -BENZAMIDE ANTICONVULSANTS | THE UPJOHN COMPANY (US) | 1987-05-07 | — | — | WO | disclosed |