Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromadoline SCHEMBL1817293 | 1.00 | MLYCD (0.46) | MLYCDHDAC3HDAC1HDAC2SSTR3 | |
| Bromadoline SCHEMBL1817292 | 1.00 | MLYCD (0.46) | MLYCDHDAC3HDAC1HDAC2SSTR3 | |
| Bromadoline SCHEMBL124529 | 0.92 | ALDH1A1 (0.46) | MLYCDHDAC3HDAC1HDAC2SSTR3 | |
| SCHEMBL11472624 | 0.87 | RAB9A (0.59) | MLYCDSSTR3TAS1R3TAS1R2TAS1R1 | |
| SCHEMBL11472627 | 0.87 | RAB9A (0.59) | MLYCDSSTR3TAS1R3TAS1R2TAS1R1 | |
| SCHEMBL11464454 | 0.86 | SSTR3 (0.58) | MLYCDSSTR3TAS1R3TAS1R2TAS1R1 | |
| SCHEMBL11465463 | 0.86 | F10 (0.52) | MLYCDTAS1R3TAS1R2TAS1R1KMT2A | |
| SCHEMBL11464453 | 0.86 | SSTR3 (0.58) | MLYCDSSTR3TAS1R3TAS1R2TAS1R1 | |
| SCHEMBL11465350 | 0.86 | F10 (0.52) | MLYCDTAS1R3TAS1R2TAS1R1KMT2A | |
| SCHEMBL10340084 | 0.85 | SSTR3 (0.48) | MLYCDSSTR3TAS1R3TAS1R2TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224566-A1 | ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES | THE UPJOHN COMPANY (US) | 1987-06-10 | — | — | EP | claimed |
| WO-1986007257-A2 | ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES | THE UPJOHN COMPANY (US) | 1986-12-18 | — | — | WO | claimed |
| US-4098904-A | ANALGESIC N-(2-AMINOCYCLOALIPHATIC)BENZAMIDES | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | claimed |
| EP-0263208-A2 | Antiarrhythmic use of aminocycloalkylamides | THE UPJOHN COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0224566-A1 | ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES | THE UPJOHN COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |
| WO-1986007257-A2 | ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES | THE UPJOHN COMPANY (US) | 1986-12-18 | — | — | WO | disclosed |
| US-4215114-A | Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]be | THE UPJOHN COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| US-4197308-A | Analgesic N-(2-heterocyclic-amino cycloaliphatic) benzamides | THE UPJOHN COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4192885-A | Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkylamino]cycloaliphatic}cyanobenzamides | THE UPJOHN COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
| US-4179501-A | Analgesic N-(2-aminocycloaliphatic)azidobenzamides | THE UPJOHN COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4153717-A | 260/332.2 R | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |
| US-4152459-A | Analgesic N-2-(aminocycloaliphatic)-hydroxy, alkoxy and (allylic)alkenyloxy-benzamides | THE UPJOHN COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4148914-A | Analgesic N-(2-aminocyclo aliphatic)cyanobenzamides | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4098904-A | ANALGESIC N-(2-AMINOCYCLOALIPHATIC)BENZAMIDES | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |