SCHEMBL1034010

SCHEMBL1034010

C1CN(CCN(CCN2CCOCC2)CCN2CCOCC2)CCO1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KEAP1 Q14145 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.45
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
DUSP3 P51452 1/20 0.41
SIGMAR1 Q99720 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
POLB P06746 1/20 0.39
ACHE P22303 1/20 0.39
HSD17B10 Q99714 2/20 0.38
DAO P14920 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27220456 0.89 KDM4E (0.57) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL31299554 0.89 KEAP1 (0.57) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL13187933 0.89 KDM4E (0.57) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL8518326 0.89 SMN1; SMN2 (0.42) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL10401216 0.86 ALDH1A1 (0.43) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL5911029 0.85 KEAP1 (0.58) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL235080 0.83 KDM4E (0.65) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL23223379 0.81 SIGMAR1 (0.40) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL5127363 0.81 SIGMAR1 (0.43) KDM4ESMN1; SMN2KEAP1ALDH1A1GLA
SCHEMBL14007432 0.81 KDM1A (0.45) KDM4ESMN1; SMN2KEAP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5064957-A Tris/morpholinoethyl/amine, Catalyst for Polyurethane Formation SAN-APRO LIMITED (JP) 1991-11-12 US claimed
JP-2243678-A None JP disclosed
JP-5239432-A None JP disclosed
US-20230383157-A1 LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES LANXESS CORPORATION (US) 2023-11-30 US disclosed
WO-2023183119-A9 SURFACE TOLERANT ADHESIVE HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2023-11-16 WO disclosed
US-20230303822-A1 Thermoset Resin Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2023-09-28 US disclosed
WO-2023183119-A2 SURFACE TOLERANT ADHESIVE HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2023-09-28 WO disclosed
EP-4214256-A1 LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES LANXESS Corporation (US) 2023-07-26 EP disclosed
EP-4200136-A1 THERMOSET RESIN COMPOSITIONS Huntsman Advanced Materials Americas LLC (US) 2023-06-28 EP disclosed
CN-115867589-A Thermosetting resin composition 亨斯迈先进材料美国有限责任公司 2023-03-28 CN disclosed
US-20030144454-A1 Polyurethane compositions based on polyester block copolymers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-07-31 US disclosed
US-20030045636-A1 Polyurethane compositions on the basis of polyester-polyether copolymers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-03-06 US disclosed
WO-2002038693-A2 UV-RESISTANT FLOCKING ADHESIVE FOR POLYMER SUBSTRATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-05-16 WO disclosed
EP-0532765-B1 MOISTURE-CURABLE HOT-MELT ADHESIVE COMPOSITION SEIKISUI CHEMICAL CO LTD (JP) 1998-06-17 EP disclosed
US-5646229-A URETHANE PREPOLYMER AND TERTIARY MORPHOLINOALKYLAMINE CURING CATALYST; HEAT RESISTANCE, BONDING STRENGTH SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-07-08 US disclosed
JP-H05239432-A MOISTURE-CURABLE POLYURETHANE ADHESIVE NIPPON SHIIKA KK 1993-09-17 JP disclosed
EP-0532765-A1 MOISTURE-CURABLE HOT-MELT ADHESIVE COMPOSITION SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-03-24 EP disclosed
US-5064957-A Tris/morpholinoethyl/amine, Catalyst for Polyurethane Formation SAN-APRO LIMITED (JP) 1991-11-12 US disclosed
US-5064957-A Tris/morpholinoethyl/amine, Catalyst for Polyurethane Formation SAN-APRO LIMITED (JP) 1991-11-12 US disclosed
JP-H02243678-A AMINE COMPOUND, ITS PRODUCTION AND URETHANIZATION REACTION CATALYST SAN APURO KK 1990-09-27 JP disclosed