Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490799 | 0.97 | ALDH1A1 (0.46) | HDAC1HDAC2ALDH1A1PKMHDAC4 | |
| SCHEMBL1752117 | 0.92 | ALDH1A1 (0.48) | HDAC1HDAC2ALDH1A1PKMMAPT | |
| Hydrogen Sulfide SCHEMBL20305480 | 0.91 | ALDH1A1 (0.47) | HDAC1HDAC2ALDH1A1PKMMAPT | |
| SCHEMBL327593 | 0.87 | HPGD (0.44) | HDAC1HDAC2ALDH1A1PKMHDAC4 | |
| SCHEMBL2002797 | 0.85 | ALDH1A1 (0.49) | ALDH1A1PKMMAPTKMT2A | |
| SCHEMBL44725 | 0.85 | ALDH1A1 (0.50) | HDAC1HDAC2ALDH1A1PKMMAPT | |
| SCHEMBL10340551 | 0.85 | ALDH1A1 (0.43) | HDAC1HDAC2ALDH1A1PKMMAPT | |
| SCHEMBL21768790 | 0.82 | ALDH1A1 (0.51) | ALDH1A1PKMMAPTKMT2A | |
| SCHEMBL28630260 | 0.80 | HDAC1 (0.41) | HDAC1HDAC2ALDH1A1PKM | |
| SCHEMBL28851780 | 0.79 | HPGD (0.55) | HDAC1HDAC2ALDH1A1PKMHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196007-B1 | DESMOSINE DERIVATIVES AND REAGENT FOR PREPARING ARTIFICIAL ANTIGENS | JAPAN TOBACCO INC. (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4841055-A | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4723012-A | Desmosine derivatives having a disulfide bond and preparation of artificial antigen using the same | JAPAN TOBACCO INC. (JP) | 1988-02-02 | — | — | US | disclosed |
| EP-0196007-A2 | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1986-10-01 | — | — | EP | disclosed |