SCHEMBL1752117

SCHEMBL1752117

O=C(O)C(CCSSc1ccccn1)N1C(=O)CCC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
PKM P14618 1/20 0.48
HDAC1 Q13547 12/20 0.39
HDAC2 Q92769 12/20 0.39
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
EHMT2 Q96KQ7 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
GLA P06280 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
NFKB1 P19838 1/20 0.36
APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL20305480 0.99 ALDH1A1 (0.47) ALDH1A1PKMHDAC1HDAC2MAPT
SCHEMBL3490799 0.93 ALDH1A1 (0.46) ALDH1A1PKMHDAC1HDAC2MAPT
SCHEMBL10340280 0.92 HDAC1 (0.47) ALDH1A1PKMHDAC1HDAC2MAPT
SCHEMBL21768790 0.88 ALDH1A1 (0.51) ALDH1A1PKMMAPTKMT2AHSD17B10
SCHEMBL44725 0.88 ALDH1A1 (0.50) ALDH1A1PKMHDAC1HDAC2MAPT
SCHEMBL28630260 0.87 HDAC1 (0.41) ALDH1A1PKMHDAC1HDAC2TP53
SCHEMBL327593 0.84 HPGD (0.44) ALDH1A1PKMHDAC1HDAC2HPGD
SCHEMBL2002797 0.83 ALDH1A1 (0.49) ALDH1A1PKMMAPTKMT2AHSD17B10
SCHEMBL16047480 0.81 HDAC1 (0.34) ALDH1A1HDAC1HDAC2MAPTKMT2A
SCHEMBL616908 0.81 ALDH1A1 (0.54) ALDH1A1PKMMAPTKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 605 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4704904-A1 TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD Tambo, Inc. (US) 2026-03-11 EP claimed
US-20260034253-A1 NECTIN-4 MINIPROTEIN CONJUGATES AKTIS ONCOLOGY INC (US) 2026-02-05 US claimed
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-02 US claimed
EP-4580684-A1 DRUG CONJUGATES OF HUMANIZED ANTI PVR ANTIBODIES Nectin Therapeutics Ltd. (IL) 2025-07-09 EP claimed
EP-4551255-A2 NECTIN-4 MINIPROTEIN CONJUGATES Aktis Oncology, Inc. (US) 2025-05-14 EP claimed
EP-4504732-A2 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF University of Connecticut (US) 2025-02-12 EP claimed
US-20250009890-A1 TRANS-CYCLOOCTENE-MODIFIED BISPECIFIC ANTIBODIES TAMBO, INC. 2025-01-09 US claimed
WO-2024249501-A2 B7H3 MINIPROTEIN CONJUGATES AKTIS ONCOLOGY, INC. (US) 2024-12-05 WO claimed
WO-2024229427-A1 TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD TAMBO, INC. (US) 2024-11-07 WO claimed
WO-2024168065-A1 SYSTEM COMPRISING MODIFIED WHOLE CELL PAYLOADS FOR TARGETED DELIVERY TAMBO, INC. (US) 2024-08-15 WO claimed
EP-2437790-B1 CONJUGATION METHODS IMMUNOGEN INC (US) 2019-02-20 EP claimed
EP-2675480-B1 METHODS OF PREPARATION OF CONJUGATES IMMUNOGEN INC (US) 2018-12-26 EP claimed
EP-2968590-B1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2018-09-05 EP claimed
US-9387261-B2 Immunoconjugates targeting CD138 and uses thereof BIOTEST AG (DE) 2016-07-12 US claimed
US-9353127-B2 Methods of preparation of conjugates IMMUNOGEN, INC. (US) 2016-05-31 US claimed
US-20160046721-A1 ANTIBODIES AND METHODS FOR TREATING ESTROGEN RECEPTOR-ASSOCIATED DISEASES BEIJING SHENOGEN PHARMA GROUP LTD. (CN) 2016-02-18 US claimed
EP-2976362-A1 ANTIBODIES AND METHODS FOR TREATING ESTROGEN RECEPTOR-ASSOCIATED DISEASES Beijing Shenogen Pharma Group Ltd. (CN) 2016-01-27 EP claimed
EP-2399609-B1 Process for preparing maytansinoid antibody conjugates IMMUNOGEN INC (US) 2015-03-18 EP claimed
WO-2014146575-A1 ANTIBODIES AND METHODS FOR TREATING ESTROGEN RECEPTOR-ASSOCIATED DISEASES BEIJING SHENOGEN PHARMA GROUP LTD. (CN) 2014-09-25 WO claimed
US-20110158991-A1 CYTOTOXIC AGENTS COMPRISING NEW MAYTANSINOIDS IMMUNOGEN INC. (US) 2011-06-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034253-A1 NECTIN-4 MINIPROTEIN CONJUGATES NECTIN4, FUT4, SDC4 ALDH1A1 4445/4885PKM 3700/4885HDAC1 3851/4885
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF JAK2, JAK1, CHMP4B ALDH1A1 1023/4885PKM 843/4885HDAC1 1946/4885
US-20250009890-A1 TRANS-CYCLOOCTENE-MODIFIED BISPECIFIC ANTIBODIES FCGR3B, PDCD10, PDCD1 ALDH1A1 4421/4885PKM 4232/4885HDAC1 3487/4885
US-20160046721-A1 ANTIBODIES AND METHODS FOR TREATING ESTROGEN RECEPTOR-ASSOCIATED DISEASES GPER1, ESRRG, ESR1 ALDH1A1 1783/4885PKM 4400/4885HDAC1 2626/4885
US-20110158991-A1 CYTOTOXIC AGENTS COMPRISING NEW MAYTANSINOIDS SPR, HCCS, TXNRD1 ALDH1A1 707/4885PKM 4503/4885HDAC1 3355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.